Skip to main content

This lesson provides an introduction to biologically detailed computational modelling of neural dynamics, including neuron membrane potential simulation and F-I curves. 

Difficulty level: Intermediate
Duration: 8:21
Speaker: : Mike X. Cohen

In this lesson, users learn how to use MATLAB to build an adaptive exponential integrate and fire (AdEx) neuron model. 

Difficulty level: Intermediate
Duration: 22:01
Speaker: : Mike X. Cohen

In this lesson, users learn about the practical differences between MATLAB scripts and functions, as well as how to embed their neuronal simulation into a callable function.  

Difficulty level: Intermediate
Duration: 11:20
Speaker: : Mike X. Cohen

This lesson teaches users how to generate a frequency-current (F-I) curve, which describes the function that relates the net synaptic current (I) flowing into a neuron to its firing rate (F). 

Difficulty level: Intermediate
Duration: 20:39
Speaker: : Mike X. Cohen

This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.

Difficulty level: Intermediate
Duration: 1:09:33
Speaker: : Sean Hill

This is the first of two workshops on reproducibility in science, during which participants are introduced to concepts of FAIR and open science. After discussing the definition of and need for FAIR science, participants are walked through tutorials on installing and using Github and Docker, the powerful, open-source tools for versioning and publishing code and software, respectively.

Difficulty level: Intermediate
Duration: 1:20:58

This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics. 

Difficulty level: Intermediate
Duration: 1:27:18
Speaker: : Dan Felsky

This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses. 

Difficulty level: Intermediate
Duration: 1:53:34
Speaker: : Dan Felsky

This tutorial demonstrates how to perform cell-type deconvolution in order to estimate how proportions of cell-types in the brain change in response to various conditions. While these techniques may be useful in addressing a wide range of scientific questions, this tutorial will focus on the cellular changes associated with major depression (MDD). 

Difficulty level: Intermediate
Duration: 1:15:14
Speaker: : Keon Arbabi

This lesson explains the fundamental principles of neuronal communication, such as neuronal spiking, membrane potentials, and cellular excitability, and how these electrophysiological features of the brain may be modelled and simulated digitally. 

Difficulty level: Intermediate
Duration: 1:20:42
Speaker: : Etay Hay

This is an in-depth guide on EEG signals and their interaction within brain microcircuits. Participants are also shown techniques and software for simulating, analyzing, and visualizing these signals.

Difficulty level: Intermediate
Duration: 1:30:41
Speaker: : Frank Mazza

This lesson describes the principles underlying functional magnetic resonance imaging (fMRI), diffusion-weighted imaging (DWI), tractography, and parcellation. These tools and concepts are explained in a broader context of neural connectivity and mental health. 

Difficulty level: Intermediate
Duration: 1:47:22

This lesson provides an overview of the current status in the field of neuroscientific ontologies, presenting examples of data organization and standards, particularly from neuroimaging and electrophysiology. 

Difficulty level: Intermediate
Duration: 33:41

This lesson continues from part one of the lecture Ontologies, Databases, and Standards, diving deeper into a description of ontologies and knowledg graphs. 

Difficulty level: Intermediate
Duration: 50:18
Speaker: : Jeff Grethe

This lesson briefly goes over the outline of the Neuroscience for Machine Learners course. 

Difficulty level: Intermediate
Duration: 3:05
Speaker: : Dan Goodman

This lesson delves into the the structure of one of the brain's most elemental computational units, the neuron, and how said structure influences computational neural network models. 

Difficulty level: Intermediate
Duration: 6:33
Speaker: : Marcus Ghosh

In this lesson you will learn how machine learners and neuroscientists construct abstract computational models based on various neurophysiological signalling properties. 

Difficulty level: Intermediate
Duration: 10:52
Speaker: : Dan Goodman

In this lesson, you will learn about some typical neuronal models employed by machine learners and computational neuroscientists, meant to imitate the biophysical properties of real neurons. 

Difficulty level: Intermediate
Duration: 3:12
Speaker: : Dan Goodman

This lesson contains practical exercises which accompanies the first few lessons of the Neuroscience for Machine Learners (Neuro4ML) course. 

Difficulty level: Intermediate
Duration: 5:58
Speaker: : Dan Goodman

This lesson goes over the basic mechanisms of neural synapses, the space between neurons where signals may be transmitted. 

Difficulty level: Intermediate
Duration: 7:03
Speaker: : Marcus Ghosh