In this lesson, the simulation of a virtual epileptic patient is presented as an example of advanced brain simulation as a translational approach to deliver improved clinical results. You will learn about the fundamentals of epilepsy, as well as the concepts underlying epilepsy simulation. By using an iPython notebook, the detailed process of this approach is explained step by step. In the end, you are able to perform simple epilepsy simulations your own.
In this lesson you will learn how to simulate seizure events and epilepsy in The Virtual Brain. We will look at the paper On the Nature of Seizure Dynamics, which describes a new local model called the Epileptor, and apply this same model in The Virtual Brain. This is part 1 of 2 in a series explaining how to use the Epileptor. In this part, we focus on setting up the parameters.
Manipulate the default connectome provided with TVB to see how structural lesions effect brain dynamics. In this hands-on session you will insert lesions into the connectome within the TVB graphical user interface (GUI). Afterwards, the modified connectome will be used for simulations and the resulting activity will be analysed using functional connectivity.
This lecture covers the emergence of cognitive science after the Second World War as an interdisciplinary field for studying the mind, with influences from anthropology, cybernetics, and artificial intelligence.
This lesson provides an introduction to neurons, synaptic transmission, and ion channels.
This lecture consists of the second half of the introduction to signal transduction, here focusing on cell receptors and signalling cascades.
This lecture gives an introduction to the types of glial cells, homeostasis (influence of cerebral blood flow and influence on neurons), insulation and protection of axons (myelin sheath; nodes of Ranvier), microglia and reactions of the CNS to injury.
Followers of this lesson wilul learn about the origin and differentiation of myelinating cell types, molecular mechanisms defining onset and progression of myelination, as well as demyelination and remyelination after injury.
This lecture covers integrating information within a network, modulating and controlling networks, functions and dysfunctions of hippocampal networks, and the integrative network controlling sleep and arousal.
This lecture focuses on the comprehension of nociception and pain sensation, highlighting how the somatosensory system and different molecular partners are involved in nociception.
This lesson discusses both state-of-the-art detection and prevention schema in working with neurodegenerative diseases.
This lesson contains both a lecture and a tutorial component. The lecture (0:00-20:03 of YouTube video) discusses both the need for intersectional approaches in healthcare as well as the impact of neglecting intersectionality in patient populations. The lecture is followed by a practical tutorial in both Python and R on how to assess intersectional bias in datasets. Links to relevant code and data are found below.
This lecture discusses what defines an integrative approach regarding research and methods, including various study designs and models which are appropriate choices when attempting to bridge data domains; a necessity when whole-person modelling.
This lecture covers an Introduction to neuron anatomy and signaling, and different types of models, including the Hodgkin-Huxley model.
This lecture covers an Introduction to neuron anatomy and signaling, and different types of models, including the Hodgkin-Huxley model.
This lecture covers an Introduction to neuron anatomy and signaling, as well as different types of models, including the Hodgkin-Huxley model.
This lecture describes non-spiking simple neuron models used in artificial neural networks and machine learning.
This lecture provides an introduction to neuron anatomy and signaling, and different types of models, including the Hodgkin-Huxley model.
This lecture describes non-spiking simple neuron models used in artificial neural networks and machine learning.
This lesson gives an introductory presentation on how data science can help with scientific reproducibility.