In this lesson, the simulation of a virtual epileptic patient is presented as an example of advanced brain simulation as a translational approach to deliver improved clinical results. You will learn about the fundamentals of epilepsy, as well as the concepts underlying epilepsy simulation. By using an iPython notebook, the detailed process of this approach is explained step by step. In the end, you are able to perform simple epilepsy simulations your own.
In this lesson you will learn how to simulate seizure events and epilepsy in The Virtual Brain. We will look at the paper On the Nature of Seizure Dynamics, which describes a new local model called the Epileptor, and apply this same model in The Virtual Brain. This is part 1 of 2 in a series explaining how to use the Epileptor. In this part, we focus on setting up the parameters.
This lecture provides an introduction to optogenetics, a biological technique to control the activity of neurons or other cell types with light.
This primer on optogenetics primer discusses how to manipulate neuronal populations with light at millisecond resolution and offers possible applications such as curing the blind and "playing the piano" with cortical neurons.
The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.
This lesson delves into the opportunities and challenges of telepsychiatry. While novel digital approaches to clinical research and care have the potential to improve and accelerate patient outcomes, researchers and care providers must consider new population factors, such as digital disparity.
This lesson provides a basic introduction to clinical presentation of schizophrenia, its etiology, and current treatment options.
The INS Emerging Issues Task Force held a virtual panel discussion on the evolving role and increased adoption of digital applications to deliver mental health care. It was held as a session at the annual conference of the Italian Society for Neuroethics.
This lecture covers visualizing extracellular neurotransmitter dynamics
This lecture consists of the second half of the introduction to signal transduction, here focusing on cell receptors and signalling cascades.
In this lesson, you will learn about GABAergic interneurons and local inhibition on the circuit level.
This lesson provides an introduction to the myriad forms of cellular mechanisms whicn underpin healthy brain function and communication.
This lesson provides an introduction to the course Cellular Mechanisms of Brain Function.
In this lesson you will learn about ion channels and the movement of ions across the cell membrane, one of the key mechanisms underlying neuronal communication.
This lesson presents the typical setup, equipment, and solutions used in whole-cell recording of neurons.
This lesson provides an introductory overview to synaptic transmission and associated neurotransmitters.
Neurodata Without Borders (NWB) is a data standard for neurophysiology that provides neuroscientists with a common standard to share, archive, use, and build common analysis tools for neurophysiology data.
This lesson provides a brief introduction to the Neuroscience Information Exchange (NIX) Format data model, which allows storing fully annotated scientific datasets, i.e., data combined with rich metadata and their relations in a consistent, comprehensive format.
In this lecture, attendees will learn how Mutant Mouse Resource and Research Center (MMRRC) archives, cryopreserves, and distributes scientifically valuable genetically engineered mouse strains and mouse ES cell lines for the genetics and biomedical research community.
This lesson provides an overview of Neurodata Without Borders (NWB), an ecosystem for neurophysiology data standardization. The lecture also introduces some NWB-enabled tools.