In this lesson, the simulation of a virtual epileptic patient is presented as an example of advanced brain simulation as a translational approach to deliver improved clinical results. You will learn about the fundamentals of epilepsy, as well as the concepts underlying epilepsy simulation. By using an iPython notebook, the detailed process of this approach is explained step by step. In the end, you are able to perform simple epilepsy simulations your own.

In this lesson you will learn how to simulate seizure events and epilepsy in The Virtual Brain. We will look at the paper On the Nature of Seizure Dynamics, which describes a new local model called the Epileptor, and apply this same model in The Virtual Brain. This is part 1 of 2 in a series explaining how to use the Epileptor. In this part, we focus on setting up the parameters.

The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.

Overview of the content for Day 1 of this course.

Overview of Day 2 of this course.

Best practices: the tips and tricks on how to get your Miniscope to work and how to get your experiments off the ground.

This talk compares various sensors and resolutions for in vivo neural recordings.

This talk delves into challenges and opportunities of Miniscope design, seeking the optimal balance between scale and function.

Attendees of this talk will learn aobut computational imaging systems and associated pipelines, as well as open-source software solutions supporting miniscope use.

This talk covers the present state and future directions of calcium imaging data analysis, particularly in the context of one-photon vs two-photon approaches. 

In this talk, results from rodent experimentation using in vivo imaging are presented, demonstrating how the monitoring of neural ensembles may reveal patterns of learning during spatial tasks.

How to start processing the raw imaging data generated with a Miniscope, including developing a usable pipeline and demoing the Minion pipeline.

The direction of miniature microscopes, including both MetaCell and other groups.

Overview of the content for Day 2 of this course.

Summary and closing remarks for this three-day course.

This hands-on tutorial explains how to run your own Minion session in the MetaCell cloud using jupityr notebooks.

In this hands-on analysis tutorial, users will mimic a kernel crash and learn the steps to restore inputs in such a case.

This lesson will go through how to extract cells from video that has been cleaned of background noise and motion.

This final hands-on analysis tutorial walks users through the last visualization steps in the cellular data.

This lecture covers infrared LED oblique illumination for studying neuronal circuits in in vitro block-preparations of the spinal cord and brain stem.