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The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.

Difficulty level: Beginner
Duration: 55:36
Speaker: : Elissa Chesler

Overview of the content for Day 1 of this course.

Difficulty level: Beginner
Duration: 00:01:59
Speaker: : Tristan Shuman

Overview of Day 2 of this course.

Difficulty level: Beginner
Duration: 00:03:28
Speaker: : Tristan Shuman

Best practices: the tips and tricks on how to get your Miniscope to work and how to get your experiments off the ground.

Difficulty level: Beginner
Duration: 00:53:34

This talk compares various sensors and resolutions for in vivo neural recordings.

Difficulty level: Beginner
Duration: 00:24:03

This talk delves into challenges and opportunities of Miniscope design, seeking the optimal balance between scale and function.

Difficulty level: Beginner
Duration: 00:21:51

Attendees of this talk will learn aobut computational imaging systems and associated pipelines, as well as open-source software solutions supporting miniscope use.

Difficulty level: Beginner
Duration: 00:17:56

This talk covers the present state and future directions of calcium imaging data analysis, particularly in the context of one-photon vs two-photon approaches. 

Difficulty level: Beginner
Duration: 00:21:06

In this talk, results from rodent experimentation using in vivo imaging are presented, demonstrating how the monitoring of neural ensembles may reveal patterns of learning during spatial tasks.

Difficulty level: Beginner
Duration: 00:19:43

How to start processing the raw imaging data generated with a Miniscope, including developing a usable pipeline and demoing the Minion pipeline.

Difficulty level: Beginner
Duration: 00:57:26

The direction of miniature microscopes, including both MetaCell and other groups.

Difficulty level: Beginner
Duration: 00:49:16

Overview of the content for Day 2 of this course.

Difficulty level: Beginner
Duration: 00:11:01
Speaker: : Tristan Shuman

Summary and closing remarks for this three-day course.

Difficulty level: Beginner
Duration: 00:04:56
Speaker: : Stephen Larson

This hands-on tutorial explains how to run your own Minion session in the MetaCell cloud using jupityr notebooks.

Difficulty level: Beginner
Duration: 01:28:03

In this hands-on analysis tutorial, users will mimic a kernel crash and learn the steps to restore inputs in such a case.

Difficulty level: Beginner
Duration: 00:20:34
Speaker: : Phil Dong

This lesson will go through how to extract cells from video that has been cleaned of background noise and motion.

Difficulty level: Beginner
Duration: 01:49:40
Speaker: : Phil Dong

This final hands-on analysis tutorial walks users through the last visualization steps in the cellular data.

Difficulty level: Beginner
Duration: 00:27:23
Speaker: : Phil Dong

This lecture covers infrared LED oblique illumination for studying neuronal circuits in in vitro block-preparations of the spinal cord and brain stem.

Difficulty level: Beginner
Duration: 25:16
Speaker: : Péter Szucs

This lecture covers the application of diffusion MRI for clinical and preclinical studies.

Difficulty level: Beginner
Duration: 33:10
Speaker: : Silvia de Santis

This brief talk goes into work being done at The Alan Turing Institute to solve real-world challenges and democratize computer vision methods to support interdisciplinary and international researchers. 

Difficulty level: Beginner
Duration: 7:10