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The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.

Difficulty level: Beginner
Duration: 55:36
Speaker: : Elissa Chesler
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This lecture covers an introduction to neuroinformatics and its subfields, the content of the short course and future neuroinformatics applications.

Difficulty level: Beginner
Duration: 34:27
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This lecture covers describing and characterizing an input-output relationship.

Difficulty level: Beginner
Duration: 1:35:33
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Part 1 of 2 of a tutorial on statistical models for neural data

Difficulty level: Beginner
Duration: 1:45:48
Speaker: : Jonathan Pillow
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Part 2 of 2 of a tutorial on statistical models for neural data.

Difficulty level: Beginner
Duration: 1:50:31
Speaker: : Jonathan Pillow
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From the retina to the superior colliculus, the lateral geniculate nucleus into primary visual cortex and beyond, this lecture gives a tour of the mammalian visual system highlighting the Nobel-prize winning discoveries of Hubel & Wiesel.

Difficulty level: Beginner
Duration: 56:31
Speaker: : Clay Reid
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From Universal Turing Machines to McCulloch-Pitts and Hopfield associative memory networks, this lecture explains what is meant by computation.

Difficulty level: Beginner
Duration: 55:27
Speaker: : Christof Koch
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Ion channels and the movement of ions across the cell membrane.

Difficulty level: Beginner
Duration: 25:51
Speaker: : Carl Petersen
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Ion channels and the movement of ions across the cell membrane.

Difficulty level: Beginner
Duration: 28:08
Speaker: : Carl Petersen
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Action potentials, and biophysics of voltage-gated ion channels.

Difficulty level: Beginner
Duration: 27:47
Speaker: : Carl Petersen
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Voltage-gating kinetics of sodium and potassium channels.

Difficulty level: Beginner
Duration: 19:20
Speaker: : Carl Petersen
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The ionic basis of the action potential, including the Hodgkin Huxley model.

Difficulty level: Beginner
Duration: 28:29
Speaker: : Carl Petersen
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Action potential initiation and propagation.

Difficulty level: Beginner
Duration: 23:16
Speaker: : Carl Petersen
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Long-range inhibitory connections in the brain, with examples from three different systems.

Difficulty level: Beginner
Duration: 19:05
Speaker: : Carl Petersen
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2nd part of the lecture. Introduction to cell receptors and signalling cascades

Difficulty level: Beginner
Duration: 41:38
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GABAergic interneurons and local inhibition on the circuit level.

Difficulty level: Beginner
Duration: 16:27
Speaker: : Carl Petersen
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Introduction to the principal of anatomical organization of neural systems in the human brain and spinal cord that mediate sensation, integrate signals, and motivate behavior.

Difficulty level: Beginner
Duration: 59:57
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This lecture focuses on the comprehension of nociception and pain sensation. It highlights how the somatosensory system and different molecular partners are involved in nociception and how nociception and pain sensation are studied in rodents and humans and the development of pain therapy.

Difficulty level: Beginner
Duration: 28:09
Speaker: : Serena Quarta
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In an overview of the structure of the mammalian neocortex, this lecture explains how the mammalian cortex is organized in a hierarchy, describing the columnar principle and canonical microcircuits

Difficulty level: Beginner
Duration: 1:02:02
Speaker: : Clay Reid
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The retina has 60 different types of neurons. What are their functions? This lecture explores the definition of cell types and their functions in the mammalian retina.

Difficulty level: Beginner
Duration: 1:07:19
Speaker: : Christof Koch