This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis, and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.
This lesson provides an overview of how to construct computational pipelines for neurophysiological data using DataJoint.
This lesson covers the ionic basis of the action potential, including the Hodgkin-Huxley model.
This lesson provides an introduction to the myriad forms of cellular mechanisms whicn underpin healthy brain function and communication.
In this lesson you will learn about the ionic basis of the action potential, including the Hodgkin-Huxley model.
This lesson provides an introduction to the course Cellular Mechanisms of Brain Function.
This lesson covers membrane potential of neurons, and how parameters around this potential have direct consequences on cellular communication at both the individual and population level.
This lesson covers the spatiotemporal dynamics of the membrane potential.
In this lesson you will learn about neurons' ability to generate signals called action potentials, and biophysics of voltage-gated ion channels.
This lesson discusses voltage-gating kinetics of sodium and potassium channels.
In this lesson, you will learn about the ionic basis of the action potential, including the Hodgkin-Huxley model.
This lesson delves into the specifics of how action potentials propagate through individual neurons.
In this lesson, you will learn about neurotransmitter release in the presynaptic specialization.
This lesson covers synaptic modulation through diffusing neurotransmitters.
This lecture gives an overview of glutamatergic transmission.
This lesson discusses glutamate release after an action potential, and the resulting post-synaptic potentials.
In this lesson, you will learn about glutamatergic excitatory neuronal circuits.
This lesson gives an overview of neurons' dendritic spines and their function.
This lecture provides an introduction GABAergic inhibition and its receptors.
This lesson takes a closer look at GABA_A receptor mediated fast inhibition.