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Manipulate the default connectome provided with TVB to see how structural lesions effect brain dynamics. In this hands-on session you will insert lesions into the connectome within the TVB graphical user interface. Afterwards the modified connectome will be used for simulations and the resulting activity will be analysed using functional connectivity.

Difficulty level: Beginner
Duration: 31:22
Speaker: : Paul Triebkorn

2nd part of the lecture. Introduction to cell receptors and signalling cascades

Difficulty level: Beginner
Duration: 41:38

GABAergic interneurons and local inhibition on the circuit level.

Difficulty level: Beginner
Duration: 16:27
Speaker: : Carl Petersen

This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.

Difficulty level: Beginner
Duration: 37:36
Speaker: : Anat Achiron

The ionic basis of the action potential, including the Hodgkin Huxley model. 

Difficulty level: Beginner
Duration: 28:29
Speaker: : Carl Petersen

Introduction to the course Cellular Mechanisms of Brain Function.

Difficulty level: Beginner
Duration: 12:20
Speaker: : Carl Petersen

The ionic basis of the action potential, including the Hodgkin Huxley model. 

Difficulty level: Beginner
Duration: 28:29
Speaker: : Carl Petersen

Introduction to the course Cellular Mechanisms of Brain Function.

Difficulty level: Beginner
Duration: 12:20
Speaker: : Carl Petersen

Ion channels and the movement of ions across the cell membrane.

Difficulty level: Beginner
Duration: 28:08
Speaker: : Carl Petersen

Spatiotemporal dynamics of the membrane potential.

Difficulty level: Beginner
Duration: 19:14
Speaker: : Carl Petersen

Action potentials, and biophysics of voltage-gated ion channels.

Difficulty level: Beginner
Duration: 27:47
Speaker: : Carl Petersen

Voltage-gating kinetics of sodium and potassium channels.

Difficulty level: Beginner
Duration: 19:20
Speaker: : Carl Petersen

The ionic basis of the action potential, including the Hodgkin Huxley model.

Difficulty level: Beginner
Duration: 28:29
Speaker: : Carl Petersen

Action potential initiation and propagation.

Difficulty level: Beginner
Duration: 23:16
Speaker: : Carl Petersen

Neurotransmitter release in the presynaptic specialization.

Difficulty level: Beginner
Duration: 21:36
Speaker: : Carl Petersen

Synaptic modulation through diffusing neurotransmitters.

Difficulty level: Beginner
Duration: 23:00
Speaker: : Carl Petersen

Glutamatergic transmission.

Difficulty level: Beginner
Duration: 28:53
Speaker: : Carl Petersen

Glutamate release after an action potential. Resulting post-synaptic potentials in a biophysically realistic situation.

Difficulty level: Beginner
Duration: 29:35
Speaker: : Carl Petersen

Glutamatergic excitatory neuronal circuits.

Difficulty level: Beginner
Duration: 28:36
Speaker: : Carl Petersen

Dendritic spines and their function.

Difficulty level: Beginner
Duration: 21:31
Speaker: : Carl Petersen