The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.
This lecture provides an introductory overview of some of the most important concepts in software engineering.
This talk describes the NIH-funded SPARC Data Structure, and how this project navigates ontology development while keeping in mind the FAIR science principles.
This lecture covers structured data, databases, federating neuroscience-relevant databases, and ontologies.
This lecture covers FAIR atlases, including their background and construction, as well as how they can be created in line with the FAIR principles.
The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.
This lesson delves into the opportunities and challenges of telepsychiatry. While novel digital approaches to clinical research and care have the potential to improve and accelerate patient outcomes, researchers and care providers must consider new population factors, such as digital disparity.
This lesson provides a basic introduction to clinical presentation of schizophrenia, its etiology, and current treatment options.
The INS Emerging Issues Task Force held a virtual panel discussion on the evolving role and increased adoption of digital applications to deliver mental health care. It was held as a session at the annual conference of the Italian Society for Neuroethics.
This lecture covers visualizing extracellular neurotransmitter dynamics
This lecture consists of the second half of the introduction to signal transduction, here focusing on cell receptors and signalling cascades.
In this lesson, you will learn about GABAergic interneurons and local inhibition on the circuit level.
This lesson discusses both state-of-the-art detection and prevention schema in working with neurodegenerative diseases.
How does the brain learn? This lecture discusses the roles of development and adult plasticity in shaping functional connectivity.
This lesson goes into the mechanisms behind changes in synaptic function created by learning.
This lecture provides an introduction to the study of eye-tracking in humans.
From the retina to the superior colliculus, the lateral geniculate nucleus into primary visual cortex and beyond, this lecture gives a tour of the mammalian visual system highlighting the Nobel-prize winning discoveries of Hubel & Wiesel.
From Universal Turing Machines to McCulloch-Pitts and Hopfield associative memory networks, this lecture explains what is meant by computation.
In an overview of the structure of the mammalian neocortex, this lecture explains how the mammalian cortex is organized in a hierarchy, describing the columnar principle and canonical microcircuits.
The retina has 60 different types of neurons. What are their functions? This lecture explores the definition of cell types and their functions in the mammalian retina.