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In this lesson, the simulation of a virtual epileptic patient is presented as an example of advanced brain simulation as a translational approach to deliver improved clinical results. You will learn about the fundamentals of epilepsy, as well as the concepts underlying epilepsy simulation. By using an iPython notebook, the detailed process of this approach is explained step by step. In the end, you are able to perform simple epilepsy simulations your own.

Difficulty level: Beginner
Duration: 1:28:53
Speaker: : Julie Courtiol

In this lesson you will learn how to simulate seizure events and epilepsy in The Virtual Brain. We will look at the paper On the Nature of Seizure Dynamics, which describes a new local model called the Epileptor, and apply this same model in The Virtual Brain. This is part 1 of 2 in a series explaining how to use the Epileptor. In this part, we focus on setting up the parameters.

Difficulty level: Beginner
Duration: 4:44
Speaker: : Paul Triebkorn
Course:

The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.

Difficulty level: Beginner
Duration: 55:36
Speaker: : Elissa Chesler

This lecture provides an introductory overview of some of the most important concepts in software engineering.

Difficulty level: Beginner
Duration: 32:59
Speaker: : Jeff Muller
Course:

This lecture covers modeling the neuron in silicon, modeling vision and audition, and sensory fusion using a deep network. 

Difficulty level: Beginner
Duration: 1:32:17
Speaker: : Shih-Chii Liu

This lesson gives an overview of past and present neurocomputing approaches and hybrid analog/digital circuits that directly emulate the properties of neurons and synapses.

Difficulty level: Beginner
Duration: 41:57
Speaker: : Giacomo Indiveri

Presentation of the Brian neural simulator, where models are defined directly by their mathematical equations and code is automatically generated for each specific target.

Difficulty level: Beginner
Duration: 20:39
Speaker: : Giacomo Indiveri

This lecture provides an introduction to optogenetics, a biological technique to control the activity of neurons or other cell types with light.

Difficulty level: Beginner
Duration: 39:34
Speaker: : Adam Packer

This primer on optogenetics primer discusses how to manipulate neuronal populations with light at millisecond resolution and offers possible applications such as curing the blind and "playing the piano" with cortical neurons.

Difficulty level: Beginner
Duration: 59:06
Speaker: : Clay Reid

This talk enumerates the challenges regarding data accessibility and reusability inherent in the current scientific publication system, and discusses novel approaches to these challenges, such as the EBRAINS Live Papers platform. 

Difficulty level: Beginner
Duration: 18:08
Speaker: : Andrew Davison

This lesson aims to define computational neuroscience in general terms, while providing specific examples of highly successful computational neuroscience projects. 

Difficulty level: Beginner
Duration: 59:21
Speaker: : Alla Borisyuk

This lesson covers membrane potential of neurons, and how parameters around this potential have direct consequences on cellular communication at both the individual and population level. 

Difficulty level: Beginner
Duration: 28:08
Speaker: : Carl Petersen

In this lesson you will learn about neurons' ability to generate signals called action potentials, and biophysics of voltage-gated ion channels.

Difficulty level: Beginner
Duration: 27:47
Speaker: : Carl Petersen

This lesson discusses voltage-gating kinetics of sodium and potassium channels.

Difficulty level: Beginner
Duration: 19:20
Speaker: : Carl Petersen

In this lesson, you will learn about the ionic basis of the action potential, including the Hodgkin-Huxley model.

Difficulty level: Beginner
Duration: 28:29
Speaker: : Carl Petersen

This lesson delves into the specifics of how action potentials propagate through individual neurons.

Difficulty level: Beginner
Duration: 23:16
Speaker: : Carl Petersen

This lesson discusses long-range inhibitory connections in the brain, with examples from three different systems.

Difficulty level: Beginner
Duration: 19:05
Speaker: : Carl Petersen
Course:

An introduction to data management, manipulation, visualization, and analysis for neuroscience. Students will learn scientific programming in Python, and use this to work with example data from areas such as cognitive-behavioral research, single-cell recording, EEG, and structural and functional MRI. Basic signal processing techniques including filtering are covered. The course includes a Jupyter Notebook and video tutorials.

 

Difficulty level: Beginner
Duration: 1:09:16
Speaker: : Aaron J. Newman

This lesson discusses both state-of-the-art detection and prevention schema in working with neurodegenerative diseases. 

Difficulty level: Beginner
Duration: 1:02:29
Speaker: : Nir Giladi

This lesson provides an overview of how to construct computational pipelines for neurophysiological data using DataJoint.

Difficulty level: Beginner
Duration: 17:37
Speaker: : Dimitri Yatsenko