Brief introduction to Research Resource Identifiers (RRIDs), persistent and unique identifiers for referencing a research resource.
Research Resource Identifiers (RRIDs) are ID numbers assigned to help researchers cite key resources (antibodies, model organisms and software projects) in the biomedical literature to improve transparency of research methods.
The Brain Imaging Data Structure (BIDS) is a standard prescribing a formal way to name and organize MRI data and metadata in a file system that simplifies communication and collaboration between users and enables easier data validation and software development through using consistent paths and naming for data files.
Neurodata Without Borders (NWB) is a data standard for neurophysiology that provides neuroscientists with a common standard to share, archive, use, and build common analysis tools for neurophysiology data.
The Neuroimaging Data Model (NIDM) is a collection of specification documents that define extensions the W3C PROV standard for the domain of human brain mapping. NIDM uses provenance information as means to link components from different stages of the scientific research process from dataset descriptors and computational workflow, to derived data and publication.
Neuroscience Information Exchange (NIX) Format data model allows storing fully annotated scientific datasets, i.e. the data together with rich metadata and their relations in a consistent, comprehensive format. Its aim is to achieve standardization by providing a common data structure and APIs for a multitude of data types and use cases, focused on but not limited to neuroscience. In contrast to most other approaches, the NIX approach is to achieve this flexibility with a minimum set of data model elements.
Computational models provide a framework for integrating data across spatial scales and for exploring hypotheses about the biological mechanisms underlying neuronal and network dynamics. However, as models increase in complexity, additional barriers emerge to the creation, exchange, and re-use of models. Successful projects have created standards for describing complex models in neuroscience and provide open source tools to address these issues. This lecture provides an overview of these projects and make a case for expanded use of resources in support of reproducibility and validation of models against experimental data.
NWB: An ecosystem for neurophysiology data standardization
This primer on optogenetics primer discusses how to manipulate neuronal populations with light at millisecond resolution and offers possible applications such as curing the blind and "playing the piano" with cortical neurons.
This lecture will highlight our current understanding and recent developments in the field of neurodegenerative disease research, as well as the future of diagnostics and treatment of neurodegenerative diseases.
2nd part of the lecture. This lecture will highlight our current understanding and recent developments in the field of neurodegenerative disease research, as well as the future of diagnostics and treatment of neurodegenerative diseases.
This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.
Most psychiatric disorders (most notably dependence syndromes, depression, psychosis, and autism) are characterized by impaired social interaction, with many patients preferring a drug of abuse. This lecture focuses on the latest research on the neural basis of normal and impaired social interaction.
This lecture will highlight our current understanding and recent developments in the field of neurodegenerative disease research, as well as the future of diagnostics and treatment of neurodegenerative diseases
This lecture provides an overview of depression (epidemiology and course of the disorder), clinical presentation, somatic co-morbidity, and treatment options.
How genetics can contribute to our understanding of psychiatric phenotypes.
The lecture focuses on rationale for employing neuroimaging methods for movement disorders
An overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the Central Nervous System.