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This lesson introduces the practical usage of The Virtual Brain (TVB) in its graphical user interface and via python scripts. In the graphical user interface, you are guided through its data repository, simulator, phase plane exploration tool, connectivity editor, stimulus generator, and the provided analyses. The implemented iPython notebooks of TVB are presented, and since they are public, can be used for further exploration of TVB. 

Difficulty level: Beginner
Duration: 1:12:24
Speaker: : Paul Triebkorn

This hands-on tutorial focuses on a brief introduction to the GUI of TVB. You will visualize a structural connectome and use it for simulation. The local neural mass model will be explored through the phase plane viewer and a parameter space exploration will be performed to observe different dynamics of the large-scale brain model.

Difficulty level: Beginner
Duration: 23:21
Speaker: : Paul Triebkorn

Simulate your own stimulation with the TVB graphical user interface. This hands-on shows you how to configure a stimulus for a specific brain region and apply it to the simulation. Afterwards the results are visualized with the TVB 3D viewer.

Difficulty level: Beginner
Duration: 20:59
Speaker: : Paul Triebkorn

Manipulate the default connectome provided with TVB to see how structural lesions effect brain dynamics. In this hands-on session you will insert lesions into the connectome within the TVB graphical user interface (GUI). Afterwards, the modified connectome will be used for simulations and the resulting activity will be analysed using functional connectivity.

Difficulty level: Beginner
Duration: 31:22
Speaker: : Paul Triebkorn

Learn how to simulate strokes with the simulation platform, The Virtual Brain. We will go through two papers: Functional Mechanisms of Recovery after Stroke: Modeling with The Virtual Brain and The Virtual Brain: Modeling Biological Correlates of Recovery After Chronic Stroke, and apply the same processes with our own structural connectivity dataset in The Virtual Brain.

Difficulty level: Beginner
Duration: 7:43
Speaker: : Paul Triebkorn

In this lesson you will learn how to simulate seizure events and epilepsy in The Virtual Brain. We will look at the paper On the Nature of Seizure Dynamics, which describes a new local model called the Epileptor, and apply this same model in The Virtual Brain. This is part 1 of 2 in a series explaining how to use the Epileptor. In this part, we focus on setting up the parameters.

Difficulty level: Beginner
Duration: 4:44
Speaker: : Paul Triebkorn

In this lecture we will focus on a paper called The Virtual Epileptic Patient: Individualized whole-brain models of epilepsy spread. We will have a closer look at the equations of the epileptor model and particular the epileptogenicity index, which controls the excitability of each brain region. Subsequently, we will begin to setup the epileptogenic zone in our own brain network model with TVB.

Difficulty level: Beginner
Duration: 6:25
Speaker: : Paul Triebkorn

After introducing the local epileptor model in the previous two videos, we will now use it in a large-scale brain simulation. We again focus on the paper The Virtual Epileptic Patient: Individualized whole-brain models of epilepsy spread. Two simulations with different epileptogenicity across the network are visualized to show the difference in seizure spread across the cortex.

Difficulty level: Beginner
Duration: 6:36
Speaker: : Paul Triebkorn

This lecture gives an overview on the article Individual brain structure and modelling predict seizure propagation, in which 15 subjects with epilepsy were modelled to predict individual epileptogenic zones. With the TVB GUI we will model seizure spread and the effect of lesioning the connectome. The impact of cutting edges in the network on seizure spreading will be visualized.

Difficulty level: Beginner
Duration: 9:39
Speaker: : Paul Triebkorn

This lecture briefly introduces The Virtual Brain (TVB), a multi-scale, multi-modal neuroinformatics platform for full brain network simulations using biologically realistic connectivity, as well as its potential neuroscience applications (e.g., epilepsy cases).

Difficulty level: Beginner
Duration: 8:53
Speaker: : Petra Ritter
Course:

The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.

Difficulty level: Beginner
Duration: 55:36
Speaker: : Elissa Chesler
Course:

Longitudinal Online Research and Imaging System (LORIS) is a web-based data and project management software for neuroimaging research studies. It is an open source framework for storing and processing behavioural, clinical, neuroimaging and genetic data. LORIS also makes it easy to manage large datasets acquired over time in a longitudinal study, or at different locations in a large multi-site study.

Difficulty level: Beginner
Duration: 0:35
Speaker: : Samir Das

This talk highlights a set of platform technologies, software, and data collections that close and shorten the feedback cycle in research. 

Difficulty level: Beginner
Duration: 57:52
Speaker: : Satrajit Ghosh

In this lecture, attendees will learn how Mutant Mouse Resource and Research Center (MMRRC) archives, cryopreserves, and distributes scientifically valuable genetically engineered mouse strains and mouse ES cell lines for the genetics and biomedical research community.

Difficulty level: Beginner
Duration: 43:38
Speaker: : Kent Lloyd

This lesson provides an overview of the database of Genotypes and Phenotypes (dbGaP), which was developed to archive and distribute the data and results from studies that have investigated the interaction of genotype and phenotype in humans.

Difficulty level: Beginner
Duration: 48:22
Speaker: : Michael Feolo

This lesson provides an overview of the process of developing the TVB-NEST co-simulation on the EBRAINS infrastructure, and its use cases.

Difficulty level: Beginner
Duration: 25:14
Speaker: : Denis Perdikis
Course:

Mozak is a scientific discovery game about neuroscience for citizen scientists and neuroscientists alike. Players to help neuroscientists build models of brain cells and learn more about the brain through their efforts.

Difficulty level: Beginner
Duration: 00:43
Speaker: : Mozak
Course:

Neuronify is an educational tool meant to create intuition for how neurons and neural networks behave. You can use it to combine neurons with different connections, just like the ones we have in our brain, and explore how changes on single cells lead to behavioral changes in important networks. Neuronify is based on an integrate-and-fire model of neurons. This is one of the simplest models of neurons that exist. It focuses on the spike timing of a neuron and ignores the details of the action potential dynamics. These neurons are modeled as simple RC circuits. When the membrane potential is above a certain threshold, a spike is generated and the voltage is reset to its resting potential. This spike then signals other neurons through its synapses.

Neuronify aims to provide a low entry point to simulation-based neuroscience.

Difficulty level: Beginner
Duration: 01:25
Speaker: : Neuronify

This lecture covers how to make modeling workflows FAIR by working through a practical example, dissecting the steps within the workflow, and detailing the tools and resources used at each step.

Difficulty level: Beginner
Duration: 15:14

This lecture will provide an overview of the INCF Training Suite, a collection of tools that embraces the FAIR principles developed by members of the INCF Community. This will include an overview of TrainingSpace, Neurostars, and KnowledgeSpace.

Difficulty level: Beginner
Duration: 09:50
Speaker: : Mathew Abrams