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In this lesson you will learn how to simulate seizure events and epilepsy in The Virtual Brain. We will look at the paper On the Nature of Seizure Dynamics, which describes a new local model called the Epileptor, and apply this same model in The Virtual Brain. This is part 1 of 2 in a series explaining how to use the Epileptor. In this part, we focus on setting up the parameters.

Difficulty level: Beginner
Duration: 4:44
Speaker: : Paul Triebkorn
Course:

The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.

Difficulty level: Beginner
Duration: 55:36
Speaker: : Elissa Chesler

In this lesson, while learning about the need for increased large-scale collaborative science that is transparent in nature, users also are given a tutorial on using Synapse for facilitating reusable and reproducible research. 

Difficulty level: Beginner
Duration: 1:15:12
Speaker: : Abhi Pratap

The lecture provides an overview of the core skills and practical solutions required to practice reproducible research.

Difficulty level: Beginner
Duration: 1:25:17
Speaker: : Fernando Perez

In this lecture, attendees will learn how Mutant Mouse Resource and Research Center (MMRRC) archives, cryopreserves, and distributes scientifically valuable genetically engineered mouse strains and mouse ES cell lines for the genetics and biomedical research community.

Difficulty level: Beginner
Duration: 43:38
Speaker: : Kent Lloyd

This lecture will provide an overview of the INCF Training Suite, a collection of tools that embraces the FAIR principles developed by members of the INCF Community. This will include an overview of TrainingSpace, Neurostars, and KnowledgeSpace.

Difficulty level: Beginner
Duration: 09:50
Speaker: : Mathew Abrams

This lesson provides an overview of GeneWeaver, a web application for the integrated cross-species analysis of functional genomics data to find convergent evidence from heterogeneous sources.

Difficulty level: Beginner
Duration: 1:03:26
Speaker: : Erich J. Baker

This lesson provides a demonstration of GeneWeaver, a system for the integration and analysis of heterogeneous functional genomics data.

Difficulty level: Beginner
Duration: 25:53
Speaker: :

This lecture outlines GeneNetwork.org, a group of linked data sets and tools used to study complex networks of genes, molecules, and higher order gene function and phenotypes.

Difficulty level: Beginner
Duration: 1:00:43
Speaker: : Robert Williams

This tutorial shows how to use the UCSC genome browser to find a list of genes in a given genomic region.

Difficulty level: Beginner
Duration: 4:32

This tutorial shows how to find all the single nucleotide polymorphisms (SNPs) upstream from genes using the UCSC Genome Browser.

Difficulty level: Beginner
Duration: 8:13

This tutorial demonstrates how to find all the single nucleotide polymorphisms (SNPs) in a gene using the UCSC Genome Browser.

Difficulty level: Beginner
Duration: 6:12

The Saved Sessions feature of the Browser has been around for quite some time, but many of our users have not made full use of it. This feature offers a great way to keep track of your thinking on a particular topic.

Difficulty level: Beginner
Duration: 7:16

The Track Collection Builder is a new tool in the UCSC Genome Browser that provides a way to create grouped collections of sub-tracks with native tracks, custom tracks, or hub tracks of continuous value graphing data types.

Difficulty level: Beginner
Duration: 2:18

This tutorial demonstrates the visibility controls on the Genome Browser, showing the effect on BED tracks, wiggle tracks, and Conservation tracks. It also discusses supertracks and composite tracks.

Difficulty level: Beginner
Duration: 14:30

This tutorial describes the isPCR tool and demonstrates how to use it for predicting the size and location of PCR products and visualizing the genomic location on the genome. The tool operates on DNA templates for all organisms, and on human and mouse DNA/RNA. It also demonstrates how to use the Browser to obtain DNA sequences from the genome.

Difficulty level: Beginner
Duration: 8:01

This tutorial describes the dbSNP resources in the UCSC Genome Browser, including display conventions and the subdivision of the data into several useful subset tracks, especially the Common SNPs. There is also a discussion about changes to the genome assemblies from one version to another, and of two ways to navigate between different assemblies of the human genome in the Browser.

Difficulty level: Beginner
Duration: 17:41

This tutorial demonstrates the UCSC Genome Browser Data Integrator, a tool that allows combination and intersection of data from up to five primary tables. In the example, data are extracted showing SNPs, genes, and phenotypes from a genomic region.

Difficulty level: Beginner
Duration: 6:24

This tutorial shows how to obtain coordinates of genes, then input those coordinates into the UCSC Genome Browser for display. The regions do not have to be continuous in the genome.

Difficulty level: Beginner
Duration: 9:04

This tutorial demonstrates the Multi-Region Exon-Only Display mode of the UCSC Genome Browser.

Difficulty level: Beginner
Duration: 5:15