The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.
This lesson provides an overview of the database of Genotypes and Phenotypes (dbGaP), which was developed to archive and distribute the data and results from studies that have investigated the interaction of genotype and phenotype in humans.
Overview of the content for Day 1 of this course.
Best practices: the tips and tricks on how to get your Miniscope to work and how to get your experiments off the ground.
This talk delves into challenges and opportunities of Miniscope design, seeking the optimal balance between scale and function.
Attendees of this talk will learn aobut computational imaging systems and associated pipelines, as well as open-source software solutions supporting miniscope use.
This talk covers the present state and future directions of calcium imaging data analysis, particularly in the context of one-photon vs two-photon approaches.
In this talk, results from rodent experimentation using in vivo imaging are presented, demonstrating how the monitoring of neural ensembles may reveal patterns of learning during spatial tasks.
How to start processing the raw imaging data generated with a Miniscope, including developing a usable pipeline and demoing the Minion pipeline.
The direction of miniature microscopes, including both MetaCell and other groups.
Overview of the content for Day 2 of this course.
Summary and closing remarks for this three-day course.
This lecture covers infrared LED oblique illumination for studying neuronal circuits in in vitro block-preparations of the spinal cord and brain stem.
This lecture covers the application of diffusion MRI for clinical and preclinical studies.
This talk covers the differences between applying HED annotation to fMRI datasets versus other neuroimaging practices, and also introduces an analysis pipeline using HED tags.
This lesson provides a thorough description of neuroimaging development over time, both conceptually and technologically. You will learn about the fundamentals of imaging techniques such as MRI and PET, as well as how the resultant data may be used to generate novel data visualization schemas.
Longitudinal Online Research and Imaging System (LORIS) is a web-based data and project management software for neuroimaging research studies. It is an open source framework for storing and processing behavioural, clinical, neuroimaging and genetic data. LORIS also makes it easy to manage large datasets acquired over time in a longitudinal study, or at different locations in a large multi-site study.
This talk covers the Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC), a free one-stop-shop collaboratory for science researchers that need resources such as neuroimaging analysis software, publicly available data sets, or computing power.
This lecture provides an introduction to reproducibility issues within the fields of neuroimaging and fMRI, as well as an overview of tools and resources being developed to alleviate the problem.
This lecture provides a historical perspective on reproducibility in science, as well as the current limitations of neuroimaging studies to date. This lecture also lays out a case for the use of meta-analyses, outlining available resources to conduct such analyses.