This lecture covers an Introduction to neuron anatomy and signaling, and different types of models, including the Hodgkin-Huxley model.
The Virtual Brain (TVB) is an open-source, multi-scale, multi-modal brain simulation platform. In this lesson, you get introduced to brain simulation in general and to TVB in particular. This lesson also presents the newest approaches for clinical applications of TVB - that is, for stroke, epilepsy, brain tumors, and Alzheimer’s disease - and show how brain simulation can improve diagnostics, therapy, and understanding of neurological disease.
This lesson explains the mathematics of neural mass models and their integration to a coupled network. You will also learn about bifurcation analysis, an important technique in the understanding of non-linear systems and as a fundamental method in the design of brain simulations. Lastly, the application of the described mathematics is demonstrated in the exploration of brain stimulation regimes.
In this lesson, the simulation of a virtual epileptic patient is presented as an example of advanced brain simulation as a translational approach to deliver improved clinical results. You will learn about the fundamentals of epilepsy, as well as the concepts underlying epilepsy simulation. By using an iPython notebook, the detailed process of this approach is explained step by step. In the end, you are able to perform simple epilepsy simulations your own.
This lecture presents the Graphical (GUI) and Command Line (CLI) User Interface of TVB. Alongside with the speakers, explore and interact with all means necessary to generate, manipulate and visualize connectivity and network dynamics.
This lecture briefly introduces The Virtual Brain (TVB), a multi-scale, multi-modal neuroinformatics platform for full brain network simulations using biologically realistic connectivity, as well as its potential neuroscience applications (e.g., epilepsy cases).
This lecture introduces the theoretical background and foundations that led to the development of TVB, its architecture, and features of its major software components.
In this lesson, you will hear about the current challenges regarding data management, as well as policies and resources aimed to address them.
In this tutorial, you will learn how to use TVB-NEST toolbox on your local computer.
This tutorial provides instruction on how to perform multi-scale simulation of Alzheimer's disease on The Virtual Brain Simulation Platform.
This lecture provides an overview of successful open-access projects aimed at describing complex neuroscientific models, and makes a case for expanded use of resources in support of reproducibility and validation of models against experimental data.
This lesson provides a brief overview of the Python programming language, with an emphasis on tools relevant to data scientists.
This lecture provides an introduction to reproducibility issues within the fields of neuroimaging and fMRI, as well as an overview of tools and resources being developed to alleviate the problem.
This lecture provides a historical perspective on reproducibility in science, as well as the current limitations of neuroimaging studies to date. This lecture also lays out a case for the use of meta-analyses, outlining available resources to conduct such analyses.
This lesson provides an overview of Neurodata Without Borders (NWB), an ecosystem for neurophysiology data standardization. The lecture also introduces some NWB-enabled tools.
This lecture on model types introduces the advantages of modeling, provide examples of different model types, and explain what modeling is all about.
This lecture summarizes the concepts introduced in Model Types I and further explains how models can be used answer different scientific questions.
This lecture focuses on how to get from a scientific question to a model using concrete examples. We will present a 10-step practical guide on how to succeed in modeling. This lecture contains links to 2 tutorials, lecture/tutorial slides, suggested reading list, and 3 recorded Q&A sessions.
This lecture formalizes modeling as a decision process that is constrained by a precise problem statement and specific model goals. We provide real-life examples on how model building is usually less linear than presented in Modeling Practice I.
This lecture focuses on the purpose of model fitting, approaches to model fitting, model fitting for linear models, and how to assess the quality and compare model fits. We will present a 10-step practical guide on how to succeed in modeling.