The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.
This lesson delves into the opportunities and challenges of telepsychiatry. While novel digital approaches to clinical research and care have the potential to improve and accelerate patient outcomes, researchers and care providers must consider new population factors, such as digital disparity.
This lecture covers a lot of post-war developments in the science of the mind, focusing first on the cognitive revolution, and concluding with living machines.
This lesson discusses both state-of-the-art detection and prevention schema in working with neurodegenerative diseases.
This lesson provides a basic introduction to clinical presentation of schizophrenia, its etiology, and current treatment options.
In this lesson, you will learn about how genetics can contribute to our understanding of psychiatric phenotypes.
This lecture provides an overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the central nervous system.
This lecture gives an introduction to the types of glial cells, homeostasis (influence of cerebral blood flow and influence on neurons), insulation and protection of axons (myelin sheath; nodes of Ranvier), microglia and reactions of the CNS to injury.
This lesson gives an introduction to simple spiking neuron models.
This lesson provides an introduction to simple spiking neuron models.
This lesson gives a primer to project management in a scientific context, with a particular neuroinformatic case study.
In this lesson, you will hear about the current challenges regarding data management, as well as policies and resources aimed to address them.
This lesson provides an overview of how to manage relationships in a research context, while highlighting the need for effective communication at various levels.
This presentation accompanies the paper entitled: An automated pipeline for constructing personalized virtual brains from multimodal neuroimaging data (see link below to download publication).
This lecture on model types introduces the advantages of modeling, provide examples of different model types, and explain what modeling is all about.
This lecture focuses on how to get from a scientific question to a model using concrete examples. We will present a 10-step practical guide on how to succeed in modeling. This lecture contains links to 2 tutorials, lecture/tutorial slides, suggested reading list, and 3 recorded Q&A sessions.
This lecture formalizes modeling as a decision process that is constrained by a precise problem statement and specific model goals. We provide real-life examples on how model building is usually less linear than presented in Modeling Practice I.
This lecture focuses on the purpose of model fitting, approaches to model fitting, model fitting for linear models, and how to assess the quality and compare model fits. We will present a 10-step practical guide on how to succeed in modeling.
This lecture summarizes the concepts introduced in Model Fitting I and adds two additional concepts: 1) MLE is a frequentist way of looking at the data and the model, with its own limitations. 2) Side-by-side comparisons of bootstrapping and cross-validation.
This lecture provides an overview of the generalized linear models (GLM) course, originally a part of the Neuromatch Academy (NMA), an interactive online summer school held in 2020. NMA provided participants with experiences spanning from hands-on modeling experience to meta-science interpretation skills across just about everything that could reasonably be included in the label "computational neuroscience".