An overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the Central Nervous System.

Difficulty level: Beginner

Duration: 45:47

Speaker: : Sandra Santos-Sierra

Course:

Introduction to simple spiking neuron models.

Difficulty level: Beginner

Duration: 48 Slides

Speaker: : Zubin Bhuyan

Introduction to simple spiking neuron models.

Difficulty level: Beginner

Duration: 48 Slides

Speaker: : Zubin Bhuyan

Course:

Introductory presentation on how data science can help with scientific reproducibility.

Difficulty level: Beginner

Duration:

Speaker: : Michel Dumontier

Course:

FAIR principles and methods currently in development for assessing FAIRness.

Difficulty level: Beginner

Duration:

Speaker: : Michel Dumontier

Audio slides presentation to accompany the paper titled: An automated pipeline for constructing personalized virtual brains from multimodal neuroimaging data. Authors: M. Schirner, S. Rothmeier, V. Jirsa, A.R. McIntosh, P. Ritter.

Difficulty level: Beginner

Duration: 4:56

Speaker: :

Course:

This lecture is part of the Neuromatch Academy (NMA), a massive, interactive online summer school held in 2020 that provided participants with experiences spanning from hands-on modeling experience to meta-science interpretation skills across just about everything that could reasonably be included in the label "computational neuroscience".

This lecture on model types introduces the advantages of modeling, provide examples of different model types, and explain what modeling is all about. This lecture contains links to 3 tutorials, lecture/tutorial slides, suggested reading list, and 3 recorded question and answer sessions.

Difficulty level: Beginner

Duration: 27:48

Speaker: : Gunnar Blohm

Course:

This lecture is part of the Neuromatch Academy (NMA), a massive, interactive online summer school held in 2020 that provided participants with experiences spanning from hands-on modeling experience to meta-science interpretation skills across just about everything that could reasonably be included in the label "computational neuroscience".

This lecture focuses on how to get from a scientific question to a model using concrete examples. We will present a 10-step practical guide on how to succeed in modeling. This lecture contains links to 2 tutorials, lecture/tutorial slides, suggested reading list, and 3 recorded question and answer sessions.

Difficulty level: Beginner

Duration: 29:52

Speaker: : Megan Peters

Course:

This lecture is part of the Neuromatch Academy (NMA), a massive, interactive online summer school held in 2020 that provided participants with experiences spanning from hands-on modeling experience to meta-science interpretation skills across just about everything that could reasonably be included in the label "computational neuroscience".

This lecture formalizes modeling as a decision process that is constrained by a precise problem statement and specific model goals. We provide real-life examples on how model building is usually less linear than presented in Modeling Practice I.

Difficulty level: Beginner

Duration: 22:51

Speaker: : Gunnar Blohm

Course:

This lecture focuses on the purpose of model fitting, approaches to model fitting, model fitting for linear models, and how to assess the quality and compare model fits. We will present a 10-step practical guide on how to succeed in modeling.

Difficulty level: Beginner

Duration: 26:46

Speaker: : Jan Drugowitsch

Course:

This lecture summarizes the concepts introduced in Model Fitting I and adds two additional concepts: 1) MLE is a frequentist way of looking at the data and the model, with its own limitations. 2) Side-by-side comparisons of bootstrapping and cross-validation.

Difficulty level: Beginner

Duration: 38.17

Speaker: : Kunlin Wei

Course:

This lecture provides an overview of generalized linear models (GLM) and contains links to 2 tutorials, lecture/tutorial slides, suggested reading list, and 3 recorded question and answer sessions.

Difficulty level: Beginner

Duration: 33:58

Speaker: : Cristina Savin

Course:

This lecture further develops the concepts introduced in Machine Learning I.

Difficulty level: Beginner

Duration: 29:30

Speaker: : I. Memming Park

Course:

This lecture introduces the core concepts of dimensionality reduction.

Difficulty level: Beginner

Duration: 31:43

Speaker: : Byron Yu

Course:

This lecture provides an application of dimensionality reduction applied to multi-dimensional neural recordings using brain-computer interfaces with simultaneous spike recordings.

Difficulty level: Beginner

Duration: 30:15

Speaker: : Byron Yu

Course:

This tutorial covers Generalized Linear Models (GLMs), which are a fundamental framework for supervised learning. In this tutorial, the objective is to model a retinal ganglion cell spike train by fitting a temporal receptive field: first with a Linear-Gaussian GLM (also known as ordinary least-squares regression model) and then with a Poisson GLM (aka "Linear-Nonlinear-Poisson" model). This tutorial also covers a special case of GLMs, logistic regression, and learn how to ensure good model performance. This tutorial is designed to run with retinal ganglion cell spike train data from Uzzell & Chichilnisky 2004.

Difficulty level: Beginner

Duration: 8:09

Speaker: : Anqi Wu

Course:

This tutorial covers multivariate data can be represented in different orthonormal bases.

Overview of this tutorial:

- Generate correlated multivariate data
- Define an arbitrary orthonormal basis
- Project the data onto the new basis

Difficulty level: Beginner

Duration: 4:48

Speaker: : Alex Cayco Gajic

Course:

This tutorial covers how to perform principal component analysis (PCA) by projecting the data onto the eigenvectors of its covariance matrix.

Overview of this tutorial:

- Calculate the eigenvectors of the sample covariance matrix.
- Perform PCA by projecting data onto the eigenvectors of the covariance matrix.
- Plot and explore the eigenvalues.

To quickly refresh your knowledge of eigenvalues and eigenvectors, you can watch this short video (4 minutes) for a geometrical explanation. For a deeper understanding, this in-depth video (17 minutes) provides an excellent basis and is beautifully illustrated.

Difficulty level: Beginner

Duration: 6:33

Speaker: : Alex Cayco Gajic

Course:

This tutorial covers how to apply principal component analysis (PCA) for dimensionality reduction, using a classic dataset that is often used to benchmark machine learning algorithms: MNIST. We'll also learn how to use PCA for reconstruction and denoising.

Overview of this tutorial:

- Perform PCA on MNIST
- Calculate the variance explained
- Reconstruct data with different numbers of PCs
- (Bonus) Examine denoising using PCA

You can learn more about MNIST dataset here.

Difficulty level: Beginner

Duration: 5:35

Speaker: : Alex Cayco Gajic

Course:

This tutorial covers how dimensionality reduction can be useful for visualizing and inferring structure in your data. To do this, we will compare principal component analysis (PCA) with t-SNE, a nonlinear dimensionality reduction method.

Overview of the tutorial:

- Visualize MNIST in 2D using PCA
- Visualize MNIST in 2D using t-SNE

Difficulty level: Beginner

Duration: 4:17

Speaker: : Alex Cayco Gajic

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