The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.
This lesson provides an overview of how to conceptualize, design, implement, and maintain neuroscientific pipelines in via the cloud-based computational reproducibility platform Code Ocean.
This lesson provides an overview of how to construct computational pipelines for neurophysiological data using DataJoint.
This talk describes approaches to maintaining integrated workflows and data management schema, taking advantage of the many open source, collaborative platforms already existing.
This hands-on tutorial walks you through DataJoint platform, highlighting features and schema which can be used to build robost neuroscientific pipelines.
This lecture provides a detailed description of how to incorporate HED annotation into your neuroimaging data pipeline.
This lesson gives an introductory presentation on how data science can help with scientific reproducibility.
This lecture covers how to make modeling workflows FAIR by working through a practical example, dissecting the steps within the workflow, and detailing the tools and resources used at each step.
The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.
This lesson delves into the opportunities and challenges of telepsychiatry. While novel digital approaches to clinical research and care have the potential to improve and accelerate patient outcomes, researchers and care providers must consider new population factors, such as digital disparity.
This lesson provides a basic introduction to clinical presentation of schizophrenia, its etiology, and current treatment options.
This lesson gives an in-depth introduction of ethics in the field of artificial intelligence, particularly in the context of its impact on humans and public interest. As the healthcare sector becomes increasingly affected by the implementation of ever stronger AI algorithms, this lecture covers key interests which must be protected going forward, including privacy, consent, human autonomy, inclusiveness, and equity.
This lesson describes a definitional framework for fairness and health equity in the age of the algorithm. While acknowledging the impressive capability of machine learning to positively affect health equity, this talk outlines potential (and actual) pitfalls which come with such powerful tools, ultimately making the case for collaborative, interdisciplinary, and transparent science as a way to operationalize fairness in health equity.
This lecture covers multiple aspects of FAIR neuroscience data: what makes it unique, the challenges to making it FAIR, the importance of overcoming these challenges, and how data governance comes into play.
This lecture provides guidance on the ethical considerations the clinical neuroimaging community faces when applying the FAIR principles to their research.
In response to a growing need in the neuroscience community for concrete guidance concerning ethically sound and pragmatically feasible open data-sharing, the CONP has created an ‘Ethics Toolkit’. These documents (links found below in 'Documents' section) are meant to help researchers identify key elements in the design and conduct of their projects that are often required for the open sharing of neuroscience data, such as model consent language and approaches to de-identification.
This guidance is the product of extended discussions and careful drafting by the CONP Ethics and Governance Committee that considers both Canadian and international ethical frameworks and research practice. The best way to cite these resources is with their associated Zenodo DOI:
Open Brain Consent is an international initiative aiming to address the challenge of creating participant consent language that will promote the open sharing of data, protect participant privacy, and conform to legal norms and institutional review boards.
Open Brain Consent addresses the aforementioned difficulties in neuroscience research with human participants by collecting: