The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.
This lecture covers a wide range of aspects regarding neuroinformatics and data governance, describing both their historical developments and current trajectories. Particular tools, platforms, and standards to make your research more FAIR are also discussed.
Introduction of the Foundations of Machine Learning in Python course - Day 01.
High-Performance Computing and Analytics Lab, University of Bonn
EyeWire is a game to map the brain. Players are challenged to map branches of a neuron from one side of a cube to the other in a 3D puzzle. Players scroll through the cube and reconstruct neurons with the help of an artificial intelligence algorithm developed at Seung Lab in Princeton University. EyeWire gameplay advances neuroscience by helping researchers discover how neurons connect to process visual information.
This lecture gives an introduction to the types of glial cells, homeostasis (influence of cerebral blood flow and influence on neurons), insulation and protection of axons (myelin sheath; nodes of Ranvier), microglia and reactions of the CNS to injury.
This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis, and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.
In this lesson, you will learn about the current challenges facing the integration of machine learning and neuroscience.
JupyterHub is a simple, highly extensible, multi-user system for managing per-user Jupyter Notebook servers, designed for research groups or classes. This lecture covers deploying JupyterHub on a single server, as well as deploying with Docker using GitHub for authentication.
This demonstration walks through how to import your data into MATLAB.
This lesson provides instruction regarding the various factors one must consider when preprocessing data, preparing it for statistical exploration and analyses.
This tutorial outlines, step by step, how to perform analysis by group and how to do change-point detection.
This tutorial walks through several common methods for visualizing your data in different ways depending on your data type.
This tutorial illustrates several ways to approach predictive modeling and machine learning with MATLAB.
This brief tutorial goes over how you can easily work with big data as you would with any size of data.
In this tutorial, you will learn how to deploy your models outside of your local MATLAB environment, enabling wider sharing and collaboration.
This lesson provides a brief overview of the Python programming language, with an emphasis on tools relevant to data scientists.
The lecture provides an overview of the core skills and practical solutions required to practice reproducible research.
This lecture covers the description and brief history of data science and its use in neuroinformatics.
This lesson provides an overview of self-supervision as it relates to neural data tasks and the Mine Your Own vieW (MYOW) approach.