Skip to main content

Computational models provide a framework for integrating data across spatial scales and for exploring hypotheses about the biological mechanisms underlying neuronal and network dynamics. However, as models increase in complexity, additional barriers emerge to the creation, exchange, and re-use of models. Successful projects have created standards for describing complex models in neuroscience and provide open source tools to address these issues. This lecture provides an overview of these projects and make a case for expanded use of resources in support of reproducibility and validation of models against experimental data.

Difficulty level: Beginner
Duration: 1:00:39
Speaker: : Sharon Crook

NWB: An ecosystem for neurophysiology data standardization

Difficulty level: Beginner
Duration: 29:53
Speaker: : Oliver Ruebel

This lecture provides an overview of depression (epidemiology and course of the disorder), clinical presentation, somatic co-morbidity, and treatment options.

Difficulty level: Beginner
Duration: 37:51

A basic introduction to clinical presentation of schizophrenia, its etiology, and current treatment options.

Difficulty level: Beginner
Duration: 51:49

This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.

Difficulty level: Beginner
Duration: 37:36
Speaker: : Anat Achiron

An overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the Central Nervous System.

Difficulty level: Beginner
Duration: 45:47

This lecture covers an Introduction to neuron anatomy and signaling, and different types of models, including the Hodgkin-Huxley model.

Difficulty level: Beginner
Duration: 1:23:01
Speaker: : Gaute Einevoll

Introductory presentation on how data science can help with scientific reproducibility.

Difficulty level: Beginner
Speaker: : Michel Dumontier