This lecture provides an introduction to the application of genetic testing in neurodevelopmental disorders.
This lesson contains both a lecture and a tutorial component. The lecture (0:00-20:03 of YouTube video) discusses both the need for intersectional approaches in healthcare as well as the impact of neglecting intersectionality in patient populations. The lecture is followed by a practical tutorial in both Python and R on how to assess intersectional bias in datasets. Links to relevant code and data are found below.
This video will document the process of uploading data into a brainlife project using ezBIDS.
This video will document the process of visualizing the provenance of each step performed to generate a data object on brainlife.
This video will document the process of downloading and running the "reproduce.sh" script, which will automatically run all of the steps to generate a data object locally on a user's machine.
This brief video walks you through the steps necessary when creating a project on brainlife.io.
This brief video rus through how to make an accout on brainlife.io.
This short video shows how data in a brainlife.io publication can be opened from a DOI inside a published article. The video provides an example of how the DOI deposited on the journal can be opened with a web browser to redirect to the associated data publication on brainlife.io.
The Allen Mouse Brain Atlas is a genome-wide, high-resolution atlas of gene expression throughout the adult mouse brain. This tutorial describes the basic search and navigation features of the Allen Mouse Brain Atlas.
The Allen Developing Mouse Brain Atlas is a detailed atlas of gene expression across mouse brain development. This tutorial describes the basic search and navigation features of the Allen Developing Mouse Brain Atlas.
This tutorial demonstrates how to use the differential search feature of the Allen Mouse Brain Atlas to find gene markers for different regions of the brain, as well as to visualize this gene expression in three-dimensional space. Differential search is also available for the Allen Developing Mouse Brain Atlas and the Allen Human Brain Atlas.
Research Resource Identifiers (RRIDs) are ID numbers assigned to help researchers cite key resources (e.g., antibodies, model organisms, and software projects) in biomedical literature to improve the transparency of research methods.
The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.
This lesson provides a demonstration of GeneWeaver, a system for the integration and analysis of heterogeneous functional genomics data.
This demonstration walks through how to import your data into MATLAB.
This lesson provides instruction regarding the various factors one must consider when preprocessing data, preparing it for statistical exploration and analyses.
This tutorial outlines, step by step, how to perform analysis by group and how to do change-point detection.
This tutorial walks through several common methods for visualizing your data in different ways depending on your data type.
This tutorial illustrates several ways to approach predictive modeling and machine learning with MATLAB.
This brief tutorial goes over how you can easily work with big data as you would with any size of data.