In this lesson, the simulation of a virtual epileptic patient is presented as an example of advanced brain simulation as a translational approach to deliver improved clinical results. You will learn about the fundamentals of epilepsy, as well as the concepts underlying epilepsy simulation. By using an iPython notebook, the detailed process of this approach is explained step by step. In the end, you are able to perform simple epilepsy simulations your own.
In this lesson you will learn how to simulate seizure events and epilepsy in The Virtual Brain. We will look at the paper On the Nature of Seizure Dynamics, which describes a new local model called the Epileptor, and apply this same model in The Virtual Brain. This is part 1 of 2 in a series explaining how to use the Epileptor. In this part, we focus on setting up the parameters.
Manipulate the default connectome provided with TVB to see how structural lesions effect brain dynamics. In this hands-on session you will insert lesions into the connectome within the TVB graphical user interface (GUI). Afterwards, the modified connectome will be used for simulations and the resulting activity will be analysed using functional connectivity.
This opening lecture from INCF's Short Course in Neuroinformatics provides an overview of the field of neuroinformatics itself, as well as laying out an argument for the necessity for developing more sophisticated approaches towards FAIR data management principles in neuroscience.
This lecture covers a wide range of aspects regarding neuroinformatics and data governance, describing both their historical developments and current trajectories. Particular tools, platforms, and standards to make your research more FAIR are also discussed.
Research Resource Identifiers (RRIDs) are ID numbers assigned to help researchers cite key resources (e.g., antibodies, model organisms, and software projects) in biomedical literature to improve the transparency of research methods.
This lecture provides an overview of successful open-access projects aimed at describing complex neuroscientific models, and makes a case for expanded use of resources in support of reproducibility and validation of models against experimental data.
This lecture gives an introduction to the FAIR (findability, accessibility, interoperability, and reusability) science principles and examples of their application in neuroscience research.
This lecture covers FAIR atlases, including their background and construction, as well as how they can be created in line with the FAIR principles.
This lecture covers why data sharing and other collaborative practices are important, how these practices are developed, and the challenges involved in their development and implementation.
This lecture covers the biomedical researcher's perspective on FAIR data sharing and the importance of finding better ways to manage large datasets.
This lecture covers the needs and challenges involved in creating a FAIR ecosystem for neuroimaging research.
This lecture covers multiple aspects of FAIR neuroscience data: what makes it unique, the challenges to making it FAIR, the importance of overcoming these challenges, and how data governance comes into play.
This lecture introduces the FAIR principles, how they relate to the field of computational neuroscience, and the resources available.
This lecture discusses how FAIR practices affect personalized data models, including workflows, challenges, and how to improve these practices.
This lecture covers how to make modeling workflows FAIR by working through a practical example, dissecting the steps within the workflow, and detailing the tools and resources used at each step.
This lecture focuses on the structured validation process within computational neuroscience, including the tools, services, and methods involved in simulation and analysis.
This lecture covers the NIDM data format within BIDS to make your datasets more searchable, and how to optimize your dataset searches.
This lecture covers the processes, benefits, and challenges involved in designing, collecting, and sharing FAIR neuroscience datasets.
This lecture covers positron emission tomography (PET) imaging and the Brain Imaging Data Structure (BIDS), and how they work together within the PET-BIDS standard to make neuroscience more open and FAIR.