Manipulate the default connectome provided with TVB to see how structural lesions effect brain dynamics. In this hands-on session you will insert lesions into the connectome within the TVB graphical user interface (GUI). Afterwards, the modified connectome will be used for simulations and the resulting activity will be analysed using functional connectivity.
Learn how to simulate strokes with the simulation platform, The Virtual Brain. We will go through two papers: Functional Mechanisms of Recovery after Stroke: Modeling with The Virtual Brain and The Virtual Brain: Modeling Biological Correlates of Recovery After Chronic Stroke, and apply the same processes with our own structural connectivity dataset in The Virtual Brain.
In this lesson you will learn how to simulate seizure events and epilepsy in The Virtual Brain. We will look at the paper On the Nature of Seizure Dynamics, which describes a new local model called the Epileptor, and apply this same model in The Virtual Brain. This is part 1 of 2 in a series explaining how to use the Epileptor. In this part, we focus on setting up the parameters.
In this lecture we will focus on a paper called The Virtual Epileptic Patient: Individualized whole-brain models of epilepsy spread. We will have a closer look at the equations of the epileptor model and particular the epileptogenicity index, which controls the excitability of each brain region. Subsequently, we will begin to setup the epileptogenic zone in our own brain network model with TVB.
After introducing the local epileptor model in the previous two videos, we will now use it in a large-scale brain simulation. We again focus on the paper The Virtual Epileptic Patient: Individualized whole-brain models of epilepsy spread. Two simulations with different epileptogenicity across the network are visualized to show the difference in seizure spread across the cortex.
This lecture gives an overview on the article Individual brain structure and modelling predict seizure propagation, in which 15 subjects with epilepsy were modelled to predict individual epileptogenic zones. With the TVB GUI we will model seizure spread and the effect of lesioning the connectome. The impact of cutting edges in the network on seizure spreading will be visualized.
This lecture presents the Graphical (GUI) and Command Line (CLI) User Interface of TVB. Alongside with the speakers, explore and interact with all means necessary to generate, manipulate and visualize connectivity and network dynamics.
This lecture briefly introduces The Virtual Brain (TVB), a multi-scale, multi-modal neuroinformatics platform for full brain network simulations using biologically realistic connectivity, as well as its potential neuroscience applications (e.g., epilepsy cases).
This lecture introduces the theoretical background and foundations that led to the development of TVB, its architecture, and features of its major software components.
This lesson provides an introduction to the Symposium on Science Management at the Canadian Association for Neuroscience 2019 Meeting.
This lesson gives a primer to project management in a scientific context, with a particular neuroinformatic case study.
In this lesson, you will hear about the current challenges regarding data management, as well as policies and resources aimed to address them.
This lesson covers "Knowledge Translation", the activities involved in moving research from the laboratory, the research journal, and the academic conference into the hands of people and organizations who can put it to practical use.
In this lesson, you will hear about the various methods developed and employed in managing performance.
This lesson provides an overview of how to manage relationships in a research context, while highlighting the need for effective communication at various levels.
This tutorial demonstrates how to use the image processing pipeline with the HBP collab.
This tutorial provides instruction on how to use the TVB-NEST toolbox co-simulation in HBP collab.
In this tutorial, you will learn how to use TVB-NEST toolbox on your local computer.
This tutorial provides instruction on how to perform multi-scale simulation of Alzheimer's disease on The Virtual Brain Simulation Platform.
This presentation accompanies the paper entitled: An automated pipeline for constructing personalized virtual brains from multimodal neuroimaging data (see link below to download publication).