This lesson discusses FAIR principles and methods currently in development for assessing FAIRness.

The Allen Mouse Brain Atlas is a genome-wide, high-resolution atlas of gene expression throughout the adult mouse brain. This tutorial describes the basic search and navigation features of the Allen Mouse Brain Atlas.

The Allen Developing Mouse Brain Atlas is a detailed atlas of gene expression across mouse brain development. This tutorial describes the basic search and navigation features of the Allen Developing Mouse Brain Atlas.

This tutorial demonstrates how to use the differential search feature of the Allen Mouse Brain Atlas to find gene markers for different regions of the brain, as well as to visualize this gene expression in three-dimensional space. Differential search is also available for the Allen Developing Mouse Brain Atlas and the Allen Human Brain Atlas.

The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.

This lesson provides a demonstration of GeneWeaver, a system for the integration and analysis of heterogeneous functional genomics data.

Introduction of the Foundations of Machine Learning in Python course - Day 01.

High-Performance Computing and Analytics Lab, University of Bonn

This lecture covers visualizing extracellular neurotransmitter dynamics

This lesson discusses both state-of-the-art detection and prevention schema in working with neurodegenerative diseases. 

This lecture provides an overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the central nervous system. 

This lesson gives an in-depth introduction of ethics in the field of artificial intelligence, particularly in the context of its impact on humans and public interest. As the healthcare sector becomes increasingly affected by the implementation of ever stronger AI algorithms, this lecture covers key interests which must be protected going forward, including privacy, consent, human autonomy, inclusiveness, and equity. 

This lesson describes a definitional framework for fairness and health equity in the age of the algorithm. While acknowledging the impressive capability of machine learning to positively affect health equity, this talk outlines potential (and actual) pitfalls which come with such powerful tools, ultimately making the case for collaborative, interdisciplinary, and transparent science as a way to operationalize fairness in health equity. 

This lecture covers multiple aspects of FAIR neuroscience data: what makes it unique, the challenges to making it FAIR, the importance of overcoming these challenges, and how data governance comes into play.

This lecture provides guidance on the ethical considerations the clinical neuroimaging community faces when applying the FAIR principles to their research. 

This module covers how neurotechnology is perceived in media today. We discuss a few specific films and talk about how the perception of neurotechnology changes with our media. Finally, we introduce a few interesting terms related to ethics and address some future issues the technology may cause.

Open Brain Consent is an international initiative aiming to address the challenge of creating participant consent language that will promote the open sharing of data, protect participant privacy, and conform to legal norms and institutional review boards.

Open Brain Consent addresses the aforementioned difficulties in neuroscience research with human participants by collecting:

• widely acceptable consent forms (with various translations) allowing deposition of anonymized data to public data archives
• collection of tools/pipelines to help anonymization of neuroimaging data making it ready for sharing