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The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.

Difficulty level: Beginner
Duration: 55:36
Speaker: : Elissa Chesler

The Allen Mouse Brain Atlas is a genome-wide, high-resolution atlas of gene expression throughout the adult mouse brain. This tutorial describes the basic search and navigation features of the Allen Mouse Brain Atlas.

Difficulty level: Beginner
Duration: 6:40

The Allen Developing Mouse Brain Atlas is a detailed atlas of gene expression across mouse brain development. This tutorial describes the basic search and navigation features of the Allen Developing Mouse Brain Atlas.

Difficulty level: Beginner
Duration: 6:35
Speaker: : Unknown

This tutorial demonstrates how to use the differential search feature of the Allen Mouse Brain Atlas to find gene markers for different regions of the brain, as well as to visualize this gene expression in three-dimensional space. Differential search is also available for the Allen Developing Mouse Brain Atlas and the Allen Human Brain Atlas.

Difficulty level: Beginner
Duration: 6:31
Speaker: : Unknown

This lecture covers FAIR atlases, including their background and construction, as well as how they can be created in line with the FAIR principles.

Difficulty level: Beginner
Duration: 14:24
Speaker: : Heidi Kleven

This lesson discusses the need for and approaches to integrating data across the various temporal and spatial scales in which brain activity can be measured. 

Difficulty level: Beginner
Duration: 1:35:37

This lesson consists of lecture and tutorial components, focusing on resources and tools which facilitate multi-scale brain modeling and simulation. 

Difficulty level: Beginner
Duration: 3:46:21

In this talk, challenges of handling complex neuroscientific data are discussed, as well as tools and services for the annotation, organization, storage, and sharing of these data. 

Difficulty level: Beginner
Duration: 21:49
Speaker: : Thomas Wachtler

This lecture describes the neuroscience data respository G-Node Infrastructure (GIN), which provides platform independent data access and enables easy data publishing. 

Difficulty level: Beginner
Duration: 22:23
Speaker: : Michael Sonntag

The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.

Difficulty level: Beginner
Duration: 1:29:28

This lesson delves into the opportunities and challenges of telepsychiatry. While novel digital approaches to clinical research and care have the potential to improve and accelerate patient outcomes, researchers and care providers must consider new population factors, such as digital disparity. 

Difficulty level: Beginner
Duration: 1:20:28
Speaker: : Abhi Pratap

This lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis, and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.

Difficulty level: Beginner
Duration: 37:36
Speaker: : Anat Achiron

This lecture will provide an overview of neuroimaging techniques and their clinical applications.

Difficulty level: Beginner
Duration: 45:29
Speaker: : Dafna Ben Bashat

This lecture picks up from the previous lesson, providing an overview of neuroimaging techniques and their clinical applications.

Difficulty level: Beginner
Duration: 41:00
Speaker: : Dafna Ben Bashat

This lesson discusses both state-of-the-art detection and prevention schema in working with neurodegenerative diseases. 

Difficulty level: Beginner
Duration: 1:02:29
Speaker: : Nir Giladi

This lecture provides an overview of depression (epidemiology and course of the disorder), clinical presentation, somatic co-morbidity, and treatment options.

Difficulty level: Beginner
Duration: 37:51

In this lesson, you will learn about how genetics can contribute to our understanding of psychiatric phenotypes.

Difficulty level: Beginner
Duration: 55:15
Speaker: : Sven Cichon

This lecture focuses on the rationale for employing neuroimaging methods for movement disorders.

Difficulty level: Beginner
Duration: 1:04:04
Speaker: : Bogdan Draganski

This lecture provides an overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the central nervous system. 

Difficulty level: Beginner
Duration: 45:47

Not long ago, scientists in physiotherapy would claim for the need of big data and large initiatives in the US have already allowed to collect large retrospective data on recovery after brain injury and are working to collect prospective data. In Europe, there is a large field of collaboration in the field of aphasia supported by the European cooperation in Science and Technology that is collecting data on language recovery throughout the world. This lecture discusses recent advances in sharing big data for neurorehabilitation.

Difficulty level: Beginner
Duration: 19:30
Speaker: : Letizia Leocani