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Computational models provide a framework for integrating data across spatial scales and for exploring hypotheses about the biological mechanisms underlying neuronal and network dynamics. However, as models increase in complexity, additional barriers emerge to the creation, exchange, and re-use of models. Successful projects have created standards for describing complex models in neuroscience and provide open source tools to address these issues. This lecture provides an overview of these projects and make a case for expanded use of resources in support of reproducibility and validation of models against experimental data.

Difficulty level: Beginner
Duration: 1:00:39
Speaker: : Sharon Crook

Introduction to the Brain Imaging Data Structure (BIDS): a standard for organizing human neuroimaging datasets. This lecture was part of the 2018 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.

Difficulty level: Intermediate
Duration: 56:49

NWB: An ecosystem for neurophysiology data standardization

Difficulty level: Beginner
Duration: 29:53
Speaker: : Oliver Ruebel

NWB: An ecosystem for neurophysiology data standardization

Difficulty level: Intermediate
Duration: 29:53
Speaker: : Oliver Ruebel

Estefany Suárez provides a conceptual overview of the rudiments of machine learning, including its bases in traditional statistics and the types of questions it might be applied to.

 

The lesson was presented in the context of the BrainHack School 2020.

Difficulty level: Beginner
Duration: 01:22:18
Speaker: :

Jake Vogel gives a hands-on, Jupyter-notebook-based tutorial to apply machine learning in Python to brain-imaging data.

 

The lesson was presented in the context of the BrainHack School 2020.

Difficulty level: Beginner
Duration: 02:13:53
Speaker: :

Gael Varoquaux presents some advanced machine learning algorithms for neuroimaging, while addressing some real-world considerations related to data size and type.

 

The lesson was presented in the context of the BrainHack School 2020.

Difficulty level: Beginner
Duration: 01:17:14
Speaker: :

Dr. Guangyu Robert Yang describes how Recurrent Neural Networks (RNNs) trained with machine learning techniques on cognitive tasks have become a widely accepted tool for neuroscientists. In comparison to traditional computational models in neuroscience, RNNs can offer substantial advantages at explaining complex behavior and neural activity patterns. Their use allows rapid generation of mechanistic hypotheses for cognitive computations. RNNs further provide a natural way to flexibly combine bottom-up biological knowledge with top-down computational goals into network models. However, early works of this approach are faced with fundamental challenges. In this talk, Dr. Guangyu Robert Yang discusses some of these challenges, and several recent steps that we took to partly address them and to build next-generation RNN models for cognitive neuroscience.​

Difficulty level: Beginner
Duration: 00:51:12
Speaker: :

Learn how to create a standard extracellular electrophysiology dataset in NWB using Python

Difficulty level: Intermediate
Duration: 23:10
Speaker: : Ryan Ly

Learn how to create a standard calcium imaging dataset in NWB using Python

Difficulty level: Intermediate
Duration: 31:04
Speaker: : Ryan Ly

Learn how to create a standard intracellular electrophysiology dataset in NWB

Difficulty level: Intermediate
Duration: 20:23
Speaker: : Pamela Baker

Learn how to use the icephys-metadata extension to enter meta-data detailing your experimental paradigm

Difficulty level: Intermediate
Duration: 27:18
Speaker: : Oliver Ruebel

Learn how to create a standard extracellular electrophysiology dataset in NWB using MATLAB

Difficulty level: Intermediate
Duration: 45:46
Speaker: : Ben Dichter

Learn how to create a standard calcium imaging dataset in NWB using MATLAB

Difficulty level: Intermediate
Duration: 39:10
Speaker: : Ben Dichter

Learn how to create a standard intracellular electrophysiology dataset in NWB

Difficulty level: Intermediate
Duration: 20:22
Speaker: : Pamela Baker

Overview of the Braintorm package for analyzing extracellular electrophysiology, including preprocessing, spike sorting, trial alignment, and spectrotemporal decomposition

Difficulty level: Intermediate
Duration: 47:47

Overview of the CaImAn package, and demonstration of usage with NWB

Difficulty level: Intermediate
Duration: 44:37

Overview of the SpikeInterface package, including demonstration of data loading, preprocessing, spike sorting, and comparison of spike sorters

Difficulty level: Intermediate
Duration: 1:10:28
Speaker: : Alessio Buccino

Overview of the NWBWidgets package, including coverage of different data types, and information for building custom widgets within this framework

Difficulty level: Intermediate
Duration: 47:15
Speaker: : Ben Dichter

Elizabeth Dupre provides reviews some standards for project management and organization, including motivation in the view of the FAIR principles and improved reproducibility.

Difficulty level: Beginner
Duration: 01:08:34
Speaker: : Elizabeth DuPre