This lecture presents the Medical Informatics Platform's data federation in epilepsy.
This lecture aims to help researchers, students, and health care professionals understand the place for neuroinformatics in the patient journey using the exemplar of an epilepsy patient.
In this lesson, the simulation of a virtual epileptic patient is presented as an example of advanced brain simulation as a translational approach to deliver improved clinical results. You will learn about the fundamentals of epilepsy, as well as the concepts underlying epilepsy simulation. By using an iPython notebook, the detailed process of this approach is explained step by step. In the end, you are able to perform simple epilepsy simulations your own.
This talk introduces data sharing initiatives in Epilepsy, particularly across Europe.
This presentation discusses the impact of data sharing in stroke.
This talks presents an overview of the potential for data federation in stroke research.
This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page.
This lesson provides a brief introduction to the Computational Modeling of Neuronal Plasticity.
In this lesson, you will be introducted to a type of neuronal model known as the leaky integrate-and-fire (LIF) model.
This lesson goes over various potential inputs to neuronal synapses, loci of neural communication.
This lesson describes the how and why behind implementing integration time steps as part of a neuronal model.
In this lesson, you will learn about neural spike trains which can be characterized as having a Poisson distribution.
This lesson covers spike-rate adaptation, the process by which a neuron's firing pattern decays to a low, steady-state frequency during the sustained encoding of a stimulus.
This lesson provides a brief explanation of how to implement a neuron's refractory period in a computational model.
In this lesson, you will learn a computational description of the process which tunes neuronal connectivity strength, spike-timing-dependent plasticity (STDP).
This lesson reviews theoretical and mathematical descriptions of correlated spike trains.
This lesson investigates the effect of correlated spike trains on spike-timing dependent plasticity (STDP).
This lesson goes over synaptic normalisation, the homeostatic process by which groups of weighted inputs scale up or down their biases.
In this lesson, you will learn about the intrinsic plasticity of single neurons.
This lesson covers short-term facilitation, a process whereby a neuron's synaptic transmission is enhanced for a short (sub-second) period.