The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.

This is the first of two workshops on reproducibility in science, during which participants are introduced to concepts of FAIR and open science. After discussing the definition of and need for FAIR science, participants are walked through tutorials on installing and using Github and Docker, the powerful, open-source tools for versioning and publishing code and software, respectively.

This lesson delves into the opportunities and challenges of telepsychiatry. While novel digital approaches to clinical research and care have the potential to improve and accelerate patient outcomes, researchers and care providers must consider new population factors, such as digital disparity. 

In this lesson, while learning about the need for increased large-scale collaborative science that is transparent in nature, users also are given a tutorial on using Synapse for facilitating reusable and reproducible research. 

This lesson describes the fundamentals of genomics, from central dogma to design and implementation of GWAS, to the computation, analysis, and interpretation of polygenic risk scores. 

This lesson contains the slides (pptx) of a lecture discussing the necessary concepts and tools for taking into account population stratification and admixture in the context of genome-wide association studies (GWAS). The free-access software Tractor and its advantages in GWAS are also discussed. 

This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes. 

This lesson describes the principles underlying functional magnetic resonance imaging (fMRI), diffusion-weighted imaging (DWI), tractography, and parcellation. These tools and concepts are explained in a broader context of neural connectivity and mental health. 

This lecture provides an introduction to Plato’s concept of rationality and Aristotle’s concept of empiricism, and the enduring discussion between rationalism and empiricism to this day.

This lecture goes into further detail about the hard problem of developing a scientific discipline for subjective consciousness.

This lecture covers the history of behaviorism and the ultimate challenge to behaviorism. 

This lecture covers various learning theories.

This lesson gives a brief introduction to the course Neuroscience for Machine Learners (Neuro4ML). 

This lesson briefly goes over the outline of the Neuroscience for Machine Learners course. 

This lesson covers the history of neuroscience and machine learning, and the story of how these two seemingly disparate fields are increasingly merging. 

In this lesson, you will learn about the current challenges facing the integration of machine learning and neuroscience. 

This lesson goes over the basic mechanisms of neural synapses, the space between neurons where signals may be transmitted. 

While the previous lesson in the Neuro4ML course dealt with the mechanisms involved in individual synapses, this lesson discusses how synapses and their neurons' firing patterns may change over time. 

This lesson delves into the human nervous system and the immense cellular, connectomic, and functional sophistication therein. 

This lesson characterizes different types of learning in a neuroscientific and cellular context, and various models employed by researchers to investigate the mechanisms involved.