Computational models provide a framework for integrating data across spatial scales and for exploring hypotheses about the biological mechanisms underlying neuronal and network dynamics. However, as models increase in complexity, additional barriers emerge to the creation, exchange, and re-use of models. Successful projects have created standards for describing complex models in neuroscience and provide open source tools to address these issues. This lecture provides an overview of these projects and make a case for expanded use of resources in support of reproducibility and validation of models against experimental data.
Introduction to the Brain Imaging Data Structure (BIDS): a standard for organizing human neuroimaging datasets. This lecture was part of the 2018 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.
NWB: An ecosystem for neurophysiology data standardization
NWB: An ecosystem for neurophysiology data standardization
DAQCORD is a framework for the design, documentation and reporting of data curation methods in order to advance the scientific rigour, reproducibility and analysis of the data. This lecture covers the rationale for developing the framework, the process in which the framework was developed, and ends with a presentation of the framework. While the driving use case for DAQCORD was clinical traumatic brain injury research, the framework is applicable to clinical studies in other domains of clinical neuroscience research.
PyNN is a simulator-independent language for building neuronal network models. The PyNN API aims to support modelling at a high-level of abstraction (populations of neurons, layers, columns and the connections between them) while still allowing access to the details of individual neurons and synapses when required. PyNN provides a library of standard neuron, synapse, and synaptic plasticity models which have been verified to work the same on the different supported simulators. PyNN also provides a set of commonly-used connectivity algorithms (e.g. all-to-all, random, distance-dependent, small-world) but makes it easy to provide your own connectivity in a simulator-independent way. This lecture was part of the 7th SpiNNaker Workshop held 3 - 6 October 2017.
This lecture and tutorial focuses on measuring human functional brain networks. The lecture and tutorial were part of the 2019 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.
A brief overview of the Python programming language, with an emphasis on tools relevant to data scientists. This lecture was part of the 2018 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.
This lecture introduces you to the basics of the Amazon Web Services public cloud. It covers the fundamentals of cloud computing and go through both motivation and process involved in moving your research computing to the cloud. This lecture was part of the 2018 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.
As models in neuroscience have become increasingly complex, it has become more difficult to share all aspects of models and model analysis, hindering model accessibility and reproducibility. In this session, we will discuss existing resources for promoting FAIR data and models in computational neuroscience, their impact on the field, and the remaining barriers. This lecture covers how FAIR practices affect personalized data models, including workflows, challenges, and how to improve these practices.
Much like neuroinformatics, data science uses techniques from computational science to derive meaningful results from large complex datasets. In this session, we will explore the relationship between neuroinformatics and data science, by emphasizing a range of data science approaches and activities, ranging from the development and application of statistical methods, through the establishment of communities and platforms, and through the implementation of open-source software tools. Rather than rigid distinctions, in the data science of neuroinformatics, these activities and approaches intersect and interact in dynamic ways. Together with a panel of cutting-edge neuro-data-scientist speakers, we will explore these dynamics
This lecture covers how brainlife.io works, and how it can be applied to neuroscience data.
Shawn Brown presents an overview of CBRAIN, a web-based platform that allows neuroscientists to perform computationally intensive data analyses by connecting them to high-performance-computing facilities across Canada and around the world.
This talk was given in the context of a Ludmer Centre event in 2019.
In this presentation by the OHBM OpenScienceSIG, Tom Shaw and Steffen Bollmann cover how containers can be useful for running the same software on different platforms and sharing analysis pipelines with other researchers. They demonstrate how to build docker containers from scratch, using Neurodocker, and cover how to use containers on an HPC with singularity.
This lecture provides an overview of depression (epidemiology and course of the disorder), clinical presentation, somatic co-morbidity, and treatment options.
Introduction to neurons, synaptic transmission, and ion channels.
Introduction to the types of glial cells, homeostasis (influence of cerebral blood flow and influence on neurons), insulation and protection of axons (myelin sheath; nodes of Ranvier), microglia and reactions of the CNS to injury.
This lecture covers: integrating information within a network, modulating and controlling networks, functions and dysfunctions of hippocampal networks, and the integrative network controlling sleep and arousal.