This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.
This lesson breaks down the principles of Bayesian inference and how it relates to cognitive processes and functions like learning and perception. It is then explained how cognitive models can be built using Bayesian statistics in order to investigate how our brains interface with their environment.
This lesson corresponds to slides 1-64 in the PDF below.
Whereas the previous two lessons described the biophysical and signalling properties of individual neurons, this lesson describes properties of those units when part of larger networks.
This lesson goes over some examples of how machine learners and computational neuroscientists go about designing and building neural network models inspired by biological brain systems.
This lecture and tutorial focuses on measuring human functional brain networks, as well as how to account for inherent variability within those networks.
This lesson continues from part one of the lecture Ontologies, Databases, and Standards, diving deeper into a description of ontologies and knowledg graphs.
This lecture covers FAIR atlases, including their background and construction, as well as how they can be created in line with the FAIR principles.
This lecture focuses on ontologies for clinical neurosciences.
This lecture describes how to build research workflows, including a demonstrate using DataJoint Elements to build data pipelines.
This lesson gives an introductory presentation on how data science can help with scientific reproducibility.
This lecture discusses how FAIR practices affect personalized data models, including workflows, challenges, and how to improve these practices.
This lecture covers how to make modeling workflows FAIR by working through a practical example, dissecting the steps within the workflow, and detailing the tools and resources used at each step.
This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication?
This lesson provides an overview of Neurodata Without Borders (NWB), an ecosystem for neurophysiology data standardization. The lecture also introduces some NWB-enabled tools.
Learn how to create a standard extracellular electrophysiology dataset in NWB using Python.
Learn how to create a standard calcium imaging dataset in NWB using Python.
In this tutorial, you will learn how to create a standard intracellular electrophysiology dataset in NWB using Python.
In this tutorial, you will learn how to use the icephys-metadata extension to enter meta-data detailing your experimental paradigm.
In this tutorial, users learn how to create a standard extracellular electrophysiology dataset in NWB using MATLAB.
Learn how to create a standard calcium imaging dataset in NWB using MATLAB.