This lecture on generating 3D brain model outside The Virtual Brain by Michael Schirner is part of the TVB Node 10 series, a 4 day workshop dedicated to learning about The Virtual Brain, brain imaging, brain simulation, personalised brain models, TVB use cases, etc... TVB is a full brain simulation platform.
Demo of the BRIAN Simulator. BRIAN is a free, open source simulator for spiking neural networks. It is written in the Python programming language and is available on almost all platforms. We believe that a simulator should not only save the time of processors, but also the time of scientists. Brian is therefore designed to be easy to learn and use, highly flexible and easily extensible.
NeuroFedora is a volunteer driven initiative to provide a ready to use Fedora based Free/Open Source Software platform for neuroscience. We believe that similar to Free Software, science should be free for all to use, share, modify, and study. The use of Free Software also aids reproducibility, data sharing, and collaboration in the research community. By making the tools used in the scientific process easier to use, NeuroFedora aims to take a step to enable this ideal. The CompNeuro Fedora Lab was specially to enable computational neuroscience. It includes everything you will need to get your work done—modelling software, analysis tools, general productivity tools—all well integrated with the modern GNOME platform to give you a complete operating system.
neurolib is a computational framework for simulating coupled neural mass models written in Python. It helps you to easily load structural brain scan data to construct brain networks where each node is a neural mass representing a single brain area. This network model can be used to simulate whole-brain dynamics. neurolib provides a simulation and optimization framework which allows you to easily implement your own neural mass model, simulate fMRI BOLD activity, analyse the results and fit your model to empirical data.
GeNN (GPU-enhanced Neuronal Networks) framework, which aims to facilitate the use of graphics accelerators for computational models of large-scale neuronal networks to address this challenge. GeNN is an open source library that generates code to accelerate the execution of network simulations on NVIDIA GPUs, through a flexible and extensible interface, which does not require in-depth technical knowledge from the users.
This video gives a short introduction to the EBRAINS data sharing platform, why it was developed, and how it contributes to open data sharing.
This video demonstrates how to find, access, and download data on EBRAINS.
Peer Herholz gives a tour of how popular virtualization tools like Docker and Singularity are playing a crucial role in improving reproducibility and enabling high-performance computing in neuroscience.
This lesson continues with the second workshop on reproducible science, focusing on additional open source tools for researchers and data scientists, such as the R programming language for data science, as well as associated tools like RStudio and R Markdown. Additionally, users are introduced to Python and iPython notebooks, Google Colab, and are given hands-on tutorials on how to create a Binder environment, as well as various containers in Docker and Singularity.
This lesson contains both a lecture and a tutorial component. The lecture (0:00-20:03 of YouTube video) discusses both the need for intersectional approaches in healthcare as well as the impact of neglecting intersectionality in patient populations. The lecture is followed by a practical tutorial in both Python and R on how to assess intersectional bias in datasets. Links to relevant code and data are found below.
This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics.
This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses.
This is a tutorial introducing participants to the basics of RNA-sequencing data and how to analyze its features using Seurat.
This tutorial demonstrates how to perform cell-type deconvolution in order to estimate how proportions of cell-types in the brain change in response to various conditions. While these techniques may be useful in addressing a wide range of scientific questions, this tutorial will focus on the cellular changes associated with major depression (MDD).
This is a tutorial on how to simulate neuronal spiking in brain microcircuit models, as well as how to analyze, plot, and visualize the corresponding data.
This tutorial talks about how to upload and version your data in OpenNeuro.org
This tutorial shows how to share your data in OpenNeuro.org
This tutorial shows how to run analysis in OpenNeuro.org
This is the first of two workshops on reproducibility in science, during which participants are introduced to concepts of FAIR and open science. After discussing the definition of and need for FAIR science, participants are walked through tutorials on installing and using Github and Docker, the powerful, open-source tools for versioning and publishing code and software, respectively.