This lesson discusses FAIR principles and methods currently in development for assessing FAIRness.
The Allen Mouse Brain Atlas is a genome-wide, high-resolution atlas of gene expression throughout the adult mouse brain. This tutorial describes the basic search and navigation features of the Allen Mouse Brain Atlas.
The Allen Developing Mouse Brain Atlas is a detailed atlas of gene expression across mouse brain development. This tutorial describes the basic search and navigation features of the Allen Developing Mouse Brain Atlas.
This tutorial demonstrates how to use the differential search feature of the Allen Mouse Brain Atlas to find gene markers for different regions of the brain, as well as to visualize this gene expression in three-dimensional space. Differential search is also available for the Allen Developing Mouse Brain Atlas and the Allen Human Brain Atlas.
The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.
This lesson provides a demonstration of GeneWeaver, a system for the integration and analysis of heterogeneous functional genomics data.
This lesson describes the principles underlying functional magnetic resonance imaging (fMRI), diffusion-weighted imaging (DWI), tractography, and parcellation. These tools and concepts are explained in a broader context of neural connectivity and mental health.
This tutorial introduces pipelines and methods to compute brain connectomes from fMRI data. With corresponding code and repositories, participants can follow along and learn how to programmatically preprocess, curate, and analyze functional and structural brain data to produce connectivity matrices.
This lesson introduces the practical exercises which accompany the previous lessons on animal and human connectomes in the brain and nervous system.
This lecture and tutorial focuses on measuring human functional brain networks, as well as how to account for inherent variability within those networks.
This tutorial demonstrates how to work with neuronal data using MATLAB, including actional potentials and spike counts, orientation tuing curves in visual cortex, and spatial maps of firing rates.
This lesson instructs users on how to import electrophysiological neural data into MATLAB, as well as how to convert spikes to a data matrix.
In this lesson, users will learn how to appropriately sort and bin neural spikes, allowing for the generation of a common and powerful visualization tool in neuroscience, the histogram.
Followers of this lesson will learn how to compute, visualize and quantify the tuning curves of individual neurons.
This lesson demonstrates how to programmatically generate a spatial map of neuronal spike counts using MATLAB.
In this lesson, users will learn about human brain signals as measured by electroencephalography (EEG), as well as associated neural signatures such as steady state visually evoked potentials (SSVEPs) and alpha oscillations.
This lecture describes the principles of EEG electrode placement in both 2- and 3-dimensional formats.
This tutorial walks users through performing Fourier Transform (FFT) spectral analysis of a single EEG channel using MATLAB.
This tutorial builds on the previous lesson's demonstration of spectral analysis of one EEG channel. Here, users will learn how to compute and visualize spectral power from all EEG channels using MATLAB.
In this lesson, users will learn more about the steady-state visually evoked potential (SSEVP), as well as how to create and interpret topographical maps derived from such studies.