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Manipulate the default connectome provided with TVB to see how structural lesions effect brain dynamics. In this hands-on session you will insert lesions into the connectome within the TVB graphical user interface. Afterwards the modified connectome will be used for simulations and the resulting activity will be analysed using functional connectivity.

Difficulty level: Beginner
Duration: 31:22
Speaker: : Paul Triebkorn
Course:

The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.

Difficulty level: Beginner
Duration: 55:36
Speaker: : Elissa Chesler
Difficulty level: Beginner
Duration: 43:38
Speaker: : Kent Lloyd
Difficulty level: Beginner
Duration: 48:22
Speaker: : Michael Feolo

An overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the Central Nervous System.

Difficulty level: Beginner
Duration: 45:47

From the retina to the superior colliculus, the lateral geniculate nucleus into primary visual cortex and beyond, this lecture gives a tour of the mammalian visual system highlighting the Nobel-prize winning discoveries of Hubel & Wiesel.

Difficulty level: Beginner
Duration: 56:31
Speaker: : Clay Reid

From Universal Turing Machines to McCulloch-Pitts and Hopfield associative memory networks, this lecture explains what is meant by computation.

Difficulty level: Beginner
Duration: 55:27
Speaker: : Christof Koch

In an overview of the structure of the mammalian neocortex, this lecture explains how the mammalian cortex is organized in a hierarchy, describing the columnar principle and canonical microcircuits

Difficulty level: Beginner
Duration: 1:02:02
Speaker: : Clay Reid

The retina has 60 different types of neurons. What are their functions? This lecture explores the definition of cell types and their functions in the mammalian retina.

Difficulty level: Beginner
Duration: 1:07:19
Speaker: : Christof Koch

Optical imaging offers a look inside the working brain. This lecture takes a look at orientation and ocular dominance columns in the visual cortex, and shows how they can be viewed with calcium imaging.

Difficulty level: Beginner
Duration: 26:17
Speaker: : Clay Reid

Functional imaging has led to the discovery of a plethora of visual cortical regions. This lecture introduces functional imaging techniques and their teachings about the visual cortex.

Difficulty level: Beginner
Duration: 1:07:03
Speaker: : Clay Reid

This lecture explains these ideas and explores the task of characterizing neuronal response properties using information theory.

Difficulty level: Beginner
Duration: 1:01:18
Speaker: : Christof Koch

What is color? This lecture explores how color is "made" in the brain and variations of color perception including trichromacy, color blindness in men, tetrachromatic vision in women, and genetic engineering of color perception.

Difficulty level: Beginner
Duration: 1:11:07
Speaker: : Christof Koch

How does the brain learn? This lecture discusses the roles of development and adult plasticity in shaping functional connectivity.

Difficulty level: Beginner
Duration: 1:08:45
Speaker: : Clay Reid

What is the difference between attention and consciousness? This lecture describes the scientific meaning of consciousness, journeys on the search for neural correlates of visual consciousness, and explores the possibility of consciousness in other beings and even non-biological structures.

Difficulty level: Beginner
Duration: 1:10:01
Speaker: : Christof Koch

This primer on optogenetics primer discusses how to manipulate neuronal populations with light at millisecond resolution and offers possible applications such as curing the blind and "playing the piano" with cortical neurons.

Difficulty level: Beginner
Duration: 59:06
Speaker: : Clay Reid