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Manipulate the default connectome provided with TVB to see how structural lesions effect brain dynamics. In this hands-on session you will insert lesions into the connectome within the TVB graphical user interface. Afterwards the modified connectome will be used for simulations and the resulting activity will be analysed using functional connectivity.

Difficulty level: Beginner
Duration: 31:22
Speaker: : Paul Triebkorn

Research Resource Identifiers (RRIDs) are ID numbers assigned to help researchers cite key resources (antibodies, model organisms and software projects) in the biomedical literature to improve transparency of research methods.

Difficulty level: Beginner
Duration: 1:01:36
Speaker: : Maryann Martone

The Brain Imaging Data Structure (BIDS) is a standard prescribing a formal way to name and organize MRI data and metadata in a file system that simplifies communication and collaboration between users and enables easier data validation and software development through using consistent paths and naming for data files.

Difficulty level: Beginner
Duration: 0:56

Neurodata Without Borders (NWB) is a data standard for neurophysiology that provides neuroscientists with a common standard to share, archive, use, and build common analysis tools for neurophysiology data.

Difficulty level: Beginner
Duration: 1:11
Speaker: : Ben Dichter

The Neuroimaging Data Model (NIDM) is a collection of specification documents that define extensions the W3C PROV standard for the domain of human brain mapping. NIDM uses provenance information as means to link components from different stages of the scientific research process from dataset descriptors and computational workflow, to derived data and publication.

Difficulty level: Beginner
Duration: 0:53

Neuroscience Information Exchange (NIX) Format data model allows storing fully annotated scientific datasets, i.e. the data together with rich metadata and their relations in a consistent, comprehensive format. Its aim is to achieve standardization by providing a common data structure and APIs for a multitude of data types and use cases, focused on but not limited to neuroscience. In contrast to most other approaches, the NIX approach is to achieve this flexibility with a minimum set of data model elements.

Difficulty level: Beginner
Duration: 1:03
Speaker: : Thomas Wachtler

Computational models provide a framework for integrating data across spatial scales and for exploring hypotheses about the biological mechanisms underlying neuronal and network dynamics. However, as models increase in complexity, additional barriers emerge to the creation, exchange, and re-use of models. Successful projects have created standards for describing complex models in neuroscience and provide open source tools to address these issues. This lecture provides an overview of these projects and make a case for expanded use of resources in support of reproducibility and validation of models against experimental data.

Difficulty level: Beginner
Duration: 1:00:39
Speaker: : Sharon Crook

KnowledgeSpace is a community-based encyclopedia that links brain research concepts to data, models, and literature. It provides users with access to anatomy, gene expression, models, morphology, and physiology data from over 15 different neuroscience data/model repositories, such as Allen Institute for Brain Science and the Human Brain Project.

Difficulty level: Beginner
Duration: 0:58
Speaker: : Tom Gillespie

The system is a central infrastructure for findable, accessible, interoperable and re-usable (FAIR) data. It provides a range of services to generate, resolve and validate persistent Compact Identifiers to promote the citability of individual data providers and integration with e-infrastructures.

Difficulty level: Beginner
Duration: 36:41

Introduction to the FAIR Principles and examples of applications of the FAIR Principles in neuroscience. This lecture was part of the 2019 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.

Difficulty level: Beginner
Duration: 55:57

Introduction to neurons, synaptic transmission, and ion channels.

Difficulty level: Beginner
Duration: 46:07

2nd part of the lecture. Introduction to cell receptors and signalling cascades

Difficulty level: Beginner
Duration: 41:38

Introduction to the types of glial cells, homeostasis (influence of cerebral blood flow and influence on neurons), insulation and protection of axons (myelin sheath; nodes of Ranvier), microglia and reactions of the CNS to injury.

Difficulty level: Beginner
Duration: 40:32

Introduction to the origin and differentiation of myelinating cell types, molecular mechanisms defining onset and progression of myelination, demyelination and remyelination after injury.

Difficulty level: Beginner
Duration: 38:52

This lecture covers: integrating information within a network, modulating and controlling networks, functions and dysfunctions of hippocampal networks, and the integrative network controlling sleep and arousal.

Difficulty level: Beginner
Duration: 47:05

This lecture focuses on the comprehension of nociception and pain sensation. It highlights how the somatosensory system and different molecular partners are involved in nociception and how nociception and pain sensation are studied in rodents and humans and the development of pain therapy.

Difficulty level: Beginner
Duration: 28:09
Speaker: : Serena Quarta

An overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the Central Nervous System.

Difficulty level: Beginner
Duration: 45:47