Skip to main content

This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page. 

Difficulty level: Intermediate
Duration: 12:50
Speaker: : Dan Goodman

This lesson provides a brief introduction to the Computational Modeling of Neuronal Plasticity.

Difficulty level: Intermediate
Duration: 0:40

In this lesson, you will be introducted to a type of neuronal model known as the leaky integrate-and-fire (LIF) model.

Difficulty level: Intermediate
Duration: 1:23

This lesson goes over various potential inputs to neuronal synapses, loci of neural communication.

Difficulty level: Intermediate
Duration: 1:20

This lesson describes the how and why behind implementing integration time steps as part of a neuronal model.

Difficulty level: Intermediate
Duration: 1:08

In this lesson, you will learn about neural spike trains which can be characterized as having a Poisson distribution.

Difficulty level: Intermediate
Duration: 1:18

This lesson covers spike-rate adaptation, the process by which a neuron's firing pattern decays to a low, steady-state frequency during the sustained encoding of a stimulus.

Difficulty level: Intermediate
Duration: 1:26

This lesson provides a brief explanation of how to implement a neuron's refractory period in a computational model.

Difficulty level: Intermediate
Duration: 0:42

In this lesson, you will learn a computational description of the process which tunes neuronal connectivity strength, spike-timing-dependent plasticity (STDP).

Difficulty level: Intermediate
Duration: 2:40

This lesson reviews theoretical and mathematical descriptions of correlated spike trains.

Difficulty level: Intermediate
Duration: 2:54

This lesson investigates the effect of correlated spike trains on spike-timing dependent plasticity (STDP).

Difficulty level: Intermediate
Duration: 1:43

This lesson goes over synaptic normalisation, the homeostatic process by which groups of weighted inputs scale up or down their biases.

Difficulty level: Intermediate
Duration: 2:58

In this lesson, you will learn about the intrinsic plasticity of single neurons.

Difficulty level: Intermediate
Duration: 2:08

This lesson covers short-term facilitation, a process whereby a neuron's synaptic transmission is enhanced for a short (sub-second) period.

Difficulty level: Intermediate
Duration: 1:58

This lesson describes short-term depression, a reduction of synaptic information transfer between neurons.

Difficulty level: Intermediate
Duration: 1:40

This lesson briefly wraps up the course on Computational Modeling of Neuronal Plasticity.

Difficulty level: Intermediate
Duration: 0:37

This lesson provides an introduction the International Neuroinformatics Coordinating Facility (INCF), its mission towards FAIR neuroscience, and future directions. 

Difficulty level: Beginner
Duration: 20:29
Speaker: : Maryann Martone

This talk describes the NIH-funded SPARC Data Structure, and how this project navigates ontology development while keeping in mind the FAIR science principles. 

Difficulty level: Beginner
Duration: 25:44
Speaker: : Fahim Imam

This is the third and final lecture of this course on neuroinformatics infrastructure for handling sensitive data. 

Difficulty level: Beginner
Duration: 1:11:22
Speaker: : Michael Schirner