This lecture provides a history of data management, recent developments data management, and a brief description of scientific data management.

This talk covers the Human Connectome Project, which aims to provide an unparalleled compilation of neural data, an interface to graphically navigate this data, and the opportunity to achieve never before realized conclusions about the living human brain.

This lesson provides instructions on how to build and share extensions in NWB.

Learn how to build custom APIs for extension.

This lesson provides instruction on advanced writing strategies in HDF5 that are accessible through PyNWB.

This lesson provides a tutorial on how to handle writing very large data in MatNWB. 

This lesson describes the fundamentals of genomics, from central dogma to design and implementation of GWAS, to the computation, analysis, and interpretation of polygenic risk scores. 

This is a hands-on tutorial on PLINK, the open source whole genome association analysis toolset. The aims of this tutorial are to teach users how to perform basic quality control on genetic datasets, as well as to identify and understand GWAS summary statistics. 

This is a tutorial on using the open-source software PRSice to calculate a set of polygenic risk scores (PRS) for a study sample. Users will also learn how to read PRS into R, visualize distributions, and perform basic association analyses. 

This lesson contains the slides (pptx) of a lecture discussing the necessary concepts and tools for taking into account population stratification and admixture in the context of genome-wide association studies (GWAS). The free-access software Tractor and its advantages in GWAS are also discussed. 

This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes. 

This is a tutorial introducing participants to the basics of RNA-sequencing data and how to analyze its features using Seurat. 

This tutorial demonstrates how to perform cell-type deconvolution in order to estimate how proportions of cell-types in the brain change in response to various conditions. While these techniques may be useful in addressing a wide range of scientific questions, this tutorial will focus on the cellular changes associated with major depression (MDD). 

Similarity Network Fusion (SNF) is a computational method for data integration across various kinds of measurements, aimed at taking advantage of the common as well as complementary information in different data types. This workshop walks participants through running SNF on EEG and genomic data using RStudio.

This lesson provides an overview of the current status in the field of neuroscientific ontologies, presenting examples of data organization and standards, particularly from neuroimaging and electrophysiology. 

This lesson continues from part one of the lecture Ontologies, Databases, and Standards, diving deeper into a description of ontologies and knowledg graphs. 

This lesson briefly goes over the outline of the Neuroscience for Machine Learners course. 

Following the previous lesson on neuronal structure, this lesson discusses neuronal function, particularly focusing on spike triggering and propogation. 

This lesson contains practical exercises which accompanies the first few lessons of the Neuroscience for Machine Learners (Neuro4ML) course. 

This lesson introduces the practical exercises which accompany the previous lessons on animal and human connectomes in the brain and nervous system.