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This book was written with the goal of introducing researchers and students in a variety of research fields to the intersection of data science and neuroimaging. This book reflects our own experience of doing research at the intersection of data science and neuroimaging and it is based on our experience working with students and collaborators who come from a variety of backgrounds and have a variety of reasons for wanting to use data science approaches in their work. The tools and ideas that we chose to write about are all tools and ideas that we have used in some way in our own research. Many of them are tools that we use on a daily basis in our work. This was important to us for a few reasons: the first is that we want to teach people things that we ourselves find useful. Second, it allowed us to write the book with a focus on solving specific analysis tasks. For example, in many of the chapters you will see that we walk you through ideas while implementing them in code, and with data. We believe that this is a good way to learn about data analysis, because it provides a connecting thread from scientific questions through the data and its representation to implementing specific answers to these questions. Finally, we find these ideas compelling and fruitful. That’s why we were drawn to them in the first place. We hope that our enthusiasm about the ideas and tools described in this book will be infectious enough to convince the readers of their value.

Difficulty level: Intermediate

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This Jupyter Book is a series of interactive tutorials about quantitative T1 mapping, powered by qMRLab. Most figures are generated with Plot.ly – you can play with them by hovering your mouse over the data, zooming in (click and drag) and out (double click), moving the sliders, and changing the drop-down options. To view the code that was used to generate the figures in this blog post, hover your cursor in the top left corner of the frame that contains the tutorial and click the checkbox “All cells” in the popup that appears.

Jupyter Lab notebooks of these tutorials are also available through MyBinder, and inline code modification inside the Jupyter Book is provided by Thebelab. For both options, you can modify the code, change the figures, and regenerate the html that was used to create the tutorial below. This Jupyter Book also uses a Script of Scripts (SoS) kernel, allowing us to process the data using qMRLab in MATLAB/Octave and plot the figures with Plot.ly using Python, all within the same Jupyter Notebook.

Difficulty level: Intermediate

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This tutorial demonstrates how to work with neuronal data using MATLAB, including actional potentials and spike counts, orientation tuing curves in visual cortex, and spatial maps of firing rates.

Difficulty level: Intermediate

Duration: 5:17

Speaker: : Mike X. Cohen

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This lesson instructs users on how to import electrophysiological neural data into MATLAB, as well as how to convert spikes to a data matrix.

Difficulty level: Intermediate

Duration: 11:37

Speaker: : Mike X. Cohen

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In this lesson, users will learn how to appropriately sort and bin neural spikes, allowing for the generation of a common and powerful visualization tool in neuroscience, the histogram.

Difficulty level: Intermediate

Duration: 5:31

Speaker: : Mike X. Cohen

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Followers of this lesson will learn how to compute, visualize and quantify the tuning curves of individual neurons.

Difficulty level: Intermediate

Duration: 13:48

Speaker: : Mike X. Cohen

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This lesson demonstrates how to programmatically generate a spatial map of neuronal spike counts using MATLAB.

Difficulty level: Intermediate

Duration: 12:16

Speaker: : Mike X. Cohen

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In this lesson, users will learn about human brain signals as measured by electroencephalography (EEG), as well as associated neural signatures such as steady state visually evoked potentials (SSVEPs) and alpha oscillations.

Difficulty level: Intermediate

Duration: 8:51

Speaker: : Mike X. Cohen

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This lecture describes the principles of EEG electrode placement in both 2- and 3-dimensional formats.

Difficulty level: Intermediate

Duration: 12:16

Speaker: : Mike X. Cohen

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This tutorial walks users through performing Fourier Transform (FFT) spectral analysis of a single EEG channel using MATLAB.

Difficulty level: Intermediate

Duration: 13:39

Speaker: : Mike X. Cohen

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This tutorial builds on the previous lesson's demonstration of spectral analysis of one EEG channel. Here, users will learn how to compute and visualize spectral power from all EEG channels using MATLAB.

Difficulty level: Intermediate

Duration: 12:34

Speaker: : Mike X. Cohen

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In this lesson, users will learn more about the steady-state visually evoked potential (SSEVP), as well as how to create and interpret topographical maps derived from such studies.

Difficulty level: Intermediate

Duration: 9:10

Speaker: : Mike X. Cohen

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This lesson teaches users how to extract edogenous brain waves from EEG data, specifically oscillations constrained to the 8-12 Hz frequency band, conventionally named alpha.

Difficulty level: Intermediate

Duration: 13:23

Speaker: : Mike X. Cohen

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In the final lesson of this module, users will learn how to correlate endogenous alpha power with SSVEP amplitude from EEG data using MATLAB.

Difficulty level: Intermediate

Duration: 12:36

Speaker: : Mike X. Cohen

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This lesson provides an introduction to biologically detailed computational modelling of neural dynamics, including neuron membrane potential simulation and F-I curves.

Difficulty level: Intermediate

Duration: 8:21

Speaker: : Mike X. Cohen

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This lesson introduces users to MATLAB live scripts; interactive documents that combine MATLAB code with formatted text, equations, and images in a single environment.

Difficulty level: Intermediate

Duration: 13:11

Speaker: : Mike X. Cohen

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In this lesson, users learn how to use MATLAB to build an adaptive exponential integrate and fire (AdEx) neuron model.

Difficulty level: Intermediate

Duration: 22:01

Speaker: : Mike X. Cohen

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In this lesson, users learn about the practical differences between MATLAB scripts and functions, as well as how to embed their neuronal simulation into a callable function.

Difficulty level: Intermediate

Duration: 11:20

Speaker: : Mike X. Cohen

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This lesson teaches users how to generate a frequency-current (F-I) curve, which describes the function that relates the net synaptic current (I) flowing into a neuron to its firing rate (F).

Difficulty level: Intermediate

Duration: 20:39

Speaker: : Mike X. Cohen

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This lecture introduces neuroscience concepts and methods such as fMRI, visual respones in BOLD data, and the eccentricity of visual receptive fields.

Difficulty level: Intermediate

Duration: 7:15

Speaker: : Mike X. Cohen

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