In this lesson, users will learn about human brain signals as measured by electroencephalography (EEG), as well as associated neural signatures such as steady state visually evoked potentials (SSVEPs) and alpha oscillations.
This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.
This lesson describes the fundamentals of genomics, from central dogma to design and implementation of GWAS, to the computation, analysis, and interpretation of polygenic risk scores.
This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes.
This is a continuation of the talk on the cellular mechanisms of neuronal communication, this time at the level of brain microcircuits and associated global signals like those measureable by electroencephalography (EEG). This lecture also discusses EEG biomarkers in mental health disorders, and how those cortical signatures may be simulated digitally.
This lecture aims to help researchers, students, and health care professionals understand the place for neuroinformatics in the patient journey using the exemplar of an epilepsy patient.
This lesson continues from part one of the lecture Ontologies, Databases, and Standards, diving deeper into a description of ontologies and knowledg graphs.
This lesson characterizes different types of learning in a neuroscientific and cellular context, and various models employed by researchers to investigate the mechanisms involved.
In this lesson, you will learn about different approaches to modeling learning in neural networks, particularly focusing on system parameters such as firing rates and synaptic weights impact a network.
This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page.
This lesson provides an overview of Jupyter notebooks, Jupyter lab, and Binder, as well as their applications within the field of neuroimaging, particularly when it comes to the writing phase of your research.
This lecture provides an introduction to entropy in general, and multi-scale entropy (MSE) in particular, highlighting the potential clinical applications of the latter.
This lecture gives an overview of how to prepare and preprocess neuroimaging (EEG/MEG) data for use in TVB.
This lecture provides an general introduction to epilepsy, as well as why and how TVB can prove useful in building and testing epileptic models.
This lesson provides a brief introduction to the Computational Modeling of Neuronal Plasticity.
In this lesson, you will be introducted to a type of neuronal model known as the leaky integrate-and-fire (LIF) model.
This lesson goes over various potential inputs to neuronal synapses, loci of neural communication.
This lesson describes the how and why behind implementing integration time steps as part of a neuronal model.
In this lesson, you will learn about neural spike trains which can be characterized as having a Poisson distribution.
This lesson covers spike-rate adaptation, the process by which a neuron's firing pattern decays to a low, steady-state frequency during the sustained encoding of a stimulus.