This is the first of two workshops on reproducibility in science, during which participants are introduced to concepts of FAIR and open science. After discussing the definition of and need for FAIR science, participants are walked through tutorials on installing and using Github and Docker, the powerful, open-source tools for versioning and publishing code and software, respectively.
This lesson describes the fundamentals of genomics, from central dogma to design and implementation of GWAS, to the computation, analysis, and interpretation of polygenic risk scores.
This lesson contains the slides (pptx) of a lecture discussing the necessary concepts and tools for taking into account population stratification and admixture in the context of genome-wide association studies (GWAS). The free-access software Tractor and its advantages in GWAS are also discussed.
This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes.
This lesson delves into the the structure of one of the brain's most elemental computational units, the neuron, and how said structure influences computational neural network models.
In this lesson you will learn how machine learners and neuroscientists construct abstract computational models based on various neurophysiological signalling properties.
While the previous lesson in the Neuro4ML course dealt with the mechanisms involved in individual synapses, this lesson discusses how synapses and their neurons' firing patterns may change over time.
This lesson characterizes different types of learning in a neuroscientific and cellular context, and various models employed by researchers to investigate the mechanisms involved.
In this lesson, you will learn about different approaches to modeling learning in neural networks, particularly focusing on system parameters such as firing rates and synaptic weights impact a network.
This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page.
In this lesson, you will learn about some of the many methods to train spiking neural networks (SNNs) with either no attempt to use gradients, or only use gradients in a limited or constrained way.
In this lesson, you will learn about one particular aspect of decision making: reaction times. In other words, how long does it take to take a decision based on a stream of information arriving continuously over time?
In this lesson, you will hear about some of the open issues in the field of neuroscience, as well as a discussion about whether neuroscience works, and how can we know?
This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication?