This lesson describes the fundamentals of genomics, from central dogma to design and implementation of GWAS, to the computation, analysis, and interpretation of polygenic risk scores.
This lesson contains the slides (pptx) of a lecture discussing the necessary concepts and tools for taking into account population stratification and admixture in the context of genome-wide association studies (GWAS). The free-access software Tractor and its advantages in GWAS are also discussed.
This lesson is an overview of transcriptomics, from fundamental concepts of the central dogma and RNA sequencing at the single-cell level, to how genetic expression underlies diversity in cell phenotypes.
Optimization for machine learning - Day 02 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Linear Algebra for Machine Learning - Day 03 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Support Vector Machines - Day 06 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Decision Trees and Random Forests - Day 07 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Clustering and Density Estimation - Day 08 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Dimensionality Reduction - Day 09 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Introduction to Neural Networks - Day 10 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Introduction to Convolutional Neural Networks - Day 11 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Initialization, Optimization, and Regularization - Day 12 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
U-Nets for medical Image-Segmentation - Day 13 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
Sequence Processing - Day 15 lecture of the Foundations of Machine Learning in Python course.
High-Performance Computing and Analytics Lab, University of Bonn
This lesson briefly goes over the outline of the Neuroscience for Machine Learners course.
This lesson goes over the basic mechanisms of neural synapses, the space between neurons where signals may be transmitted.
While the previous lesson in the Neuro4ML course dealt with the mechanisms involved in individual synapses, this lesson discusses how synapses and their neurons' firing patterns may change over time.
This lesson characterizes different types of learning in a neuroscientific and cellular context, and various models employed by researchers to investigate the mechanisms involved.
In this lesson, you will learn about different approaches to modeling learning in neural networks, particularly focusing on system parameters such as firing rates and synaptic weights impact a network.
As the previous lesson of this course described how researchers acquire neural data, this lesson will discuss how to go about interpreting and analysing the data.