This lesson teaches users how to generate a frequency-current (F-I) curve, which describes the function that relates the net synaptic current (I) flowing into a neuron to its firing rate (F).
This lecture introduces neuroscience concepts and methods such as fMRI, visual respones in BOLD data, and the eccentricity of visual receptive fields.
This tutorial walks users through the creation and visualization of activation flat maps from fMRI datasets.
This tutorial demonstrates to users the conventional preprocessing steps when working with BOLD signal datasets from fMRI.
In this tutorial, users will learn how to create a trial-averaged BOLD response and store it in a matrix in MATLAB.
This tutorial teaches users how to create animations of BOLD responses over time, to allow researchers and clinicians to visualize time-course activity patterns.
This tutorial demonstrates how to use MATLAB to create event-related BOLD time courses from fMRI datasets.
In this tutorial, users learn how to compute and visualize a t-test on experimental condition differences.
This lesson introduces various methods in MATLAB useful for dealing with data generated by calcium imaging.
This tutorial demonstrates how to use MATLAB to generate and visualize animations of calcium fluctuations over time.
This tutorial instructs users how to use MATLAB to programmatically convert data from cells to a matrix.
In this tutorial, users will learn how to identify and remove background noise, or "blur", an important step in isolating cell bodies from image data.
This lesson teaches users how MATLAB can be used to apply image processing techniques to identify cell bodies based on contiguity.
This tutorial demonstrates how to extract the time course of calcium activity from each clusters of neuron somata, and store the data in a MATLAB matrix.
This lesson demonstrates how to use MATLAB to implement a multivariate dimension reduction method, PCA, on time series data.
This is a tutorial introducing participants to the basics of RNA-sequencing data and how to analyze its features using Seurat.
This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.
This is a continuation of the talk on the cellular mechanisms of neuronal communication, this time at the level of brain microcircuits and associated global signals like those measureable by electroencephalography (EEG). This lecture also discusses EEG biomarkers in mental health disorders, and how those cortical signatures may be simulated digitally.
This lecture aims to help researchers, students, and health care professionals understand the place for neuroinformatics in the patient journey using the exemplar of an epilepsy patient.
This lecture provides an introduction to entropy in general, and multi-scale entropy (MSE) in particular, highlighting the potential clinical applications of the latter.