This lesson describes the principles underlying functional magnetic resonance imaging (fMRI), diffusion-weighted imaging (DWI), tractography, and parcellation. These tools and concepts are explained in a broader context of neural connectivity and mental health. 

This lesson introduces the practical exercises which accompany the previous lessons on animal and human connectomes in the brain and nervous system. 

This lecture presents an overview of functional brain parcellations, as well as a set of tutorials on bootstrap agregation of stable clusters (BASC) for fMRI brain parcellation.

Optimization for machine learning - Day 02 lecture of the Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

Linear Algebra for Machine Learning - Day 03 lecture of the Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

Support Vector Machines -  Day 06 lecture of the  Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

Decision Trees and Random Forests -  Day 07 lecture of the  Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

Clustering and Density Estimation -  Day 08 lecture of the  Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

Dimensionality Reduction -  Day 09 lecture of the  Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

Introduction to Neural Networks -  Day 10 lecture of the  Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

Introduction to Convolutional Neural Networks  -  Day 11 lecture of the  Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

Initialization, Optimization, and Regularization  -  Day 12 lecture of the  Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

U-Nets for medical Image-Segmentation  -  Day 13 lecture of the  Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

Sequence Processing -  Day 15 lecture of the  Foundations of Machine Learning in Python course.

High-Performance Computing and Analytics Lab, University of Bonn

This is a continuation of the talk on the cellular mechanisms of neuronal communication, this time at the level of brain microcircuits and associated global signals like those measureable by electroencephalography (EEG). This lecture also discusses EEG biomarkers in mental health disorders, and how those cortical signatures may be simulated digitally.

This lesson goes over the basic mechanisms of neural synapses, the space between neurons where signals may be transmitted. 

This lesson describes spike timing-dependent plasticity (STDP), a biological process that adjusts the strength of connections between neurons in the brain, and how one can implement or mimic this process in a computational model. You will also find links for practical exercises at the bottom of this page. 

This lesson discusses a gripping neuroscientific question: why have neurons developed the discrete action potential, or spike, as a principle method of communication? 

This lesson is a general overview of overarching concepts in neuroinformatics research, with a particular focus on clinical approaches to defining, measuring, studying, diagnosing, and treating various brain disorders. Also described are the complex, multi-level nature of brain disorders and the data associated with them, from genes and individual cells up to cortical microcircuits and whole-brain network dynamics. Given the heterogeneity of brain disorders and their underlying mechanisms, this lesson lays out a case for multiscale neuroscience data integration.

This lesson explains the fundamental principles of neuronal communication, such as neuronal spiking, membrane potentials, and cellular excitability, and how these electrophysiological features of the brain may be modelled and simulated digitally.