The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.

GeneWeaver is a web application for the integrated cross-species analysis of functional genomics data to find convergent evidence from heterogeneous sources. The application consists of a large database of gene sets curated from multiple public data resources and curated submissions, along with a suite of analysis tools designed to allow flexible, customized workflows through web-based interactive analysis or scripted API driven analysis. Gene sets come from multiple widely studied species and include ontology annotations, brain gene expression atlases, systems genetic study results, gene regulatory information, pathway databases, drug interaction databases and many other sources. Users can retrieve, store, analyze and share gene sets through a graded access system. Analysis tools are based on combinatorics and statistical methods for comparing, contrasting, and classifying gene sets based on their members.

GeneWeaver is a web application for the integrated cross-species analysis of functional genomics data to find convergent evidence from heterogeneous sources. The application consists of a large database of gene sets curated from multiple public data resources and curated submissions, along with a suite of analysis tools designed to allow flexible, customized workflows through web-based interactive analysis or scripted API driven analysis. Gene sets come from multiple widely studied species and include ontology annotations, brain gene expression atlases, systems genetic study results, gene regulatory information, pathway databases, drug interaction databases and many other sources. Users can retrieve, store, analyze and share gene sets through a graded access system. Analysis tools are based on combinatorics and statistical methods for comparing, contrasting and classifying gene sets based on their members.

Longitudinal Online Research and Imaging System (LORIS) is a web-based data and project management software for neuroimaging research studies. It is an open source framework for storing and processing behavioural, clinical, neuroimaging and genetic data. LORIS also makes it easy to manage large datasets acquired over time in a longitudinal study, or at different locations in a large multi-site study.

This talk highlights a set of platform technologies, software, and data collections that close and shorten the feedback cycle in research. 

An agent for reproducible neuroimaging

The Identifiers.org system is a central infrastructure for findable, accessible, interoperable and re-usable (FAIR) data. It provides a range of services to generate, resolve and validate persistent Compact Identifiers to promote the citability of individual data providers and integration with e-infrastructures.

This lecture covers how FAIR practices affect personalized data models, including workflows, challenges, and how to improve these practices.

This lecture covers how brainlife.io works, and how it can be applied to neuroscience data.

As a part of NeuroHackademy 2020, Tara Madhyastha (University of Washington), Andrew Crabb (AWS), and Ariel Rokem (University of Washington) give a lecture on Cloud Computing, focusing on Amazon Web Services. 

This video is provided by the University of Washington eScience Institute.

Shawn Brown presents an overview of CBRAIN, a web-based platform that allows neuroscientists to perform computationally intensive data analyses by connecting them to high-performance-computing facilities across Canada and around the world.

This talk was given in the context of a Ludmer Centre event in 2019.

Since their introduction in 2016, the FAIR data principles have gained increasing recognition and adoption in global neuroscience.  FAIR defines a set of high-level principles and practices for making digital objects, including data, software, and workflows, Findable, Accessible,  Interoperable, and Reusable.  But FAIR is not a specification;  it leaves many of the specifics up to individual scientific disciplines to define.  INCF has been leading the way in promoting, defining, and implementing FAIR data practices for neuroscience.  We have been bringing together researchers, infrastructure providers, industry, and publishers through our programs and networks.  In this session, we will hear some perspectives on FAIR neuroscience from some of these stakeholders who have been working to develop and use FAIR tools for neuroscience.  We will engage in a discussion on questions such as:  how is neuroscience doing with respect to FAIR?  What have been the successes?  What is currently very difficult? Where does neuroscience need to go?

This lecture covers FAIR atlases, from their background, their construction, and how they can be created in line with the FAIR principles.

Serving as good refresher, Shawn Grooms explains the maths and logic concepts that are important for programmers to understand, including sets, propositional logic, conditional statements, and more.

This compilation is courtesy of freeCodeCamp.

Linear algebra is the branch of mathematics concerning linear equations such as linear functions and their representations through matrices and vector spaces. As such, it underlies a huge variety of analyses in the neurosciences.  This lesson provides a useful refresher which will facilitate the use of Matlab, Octave, and various matrix-manipulation and machine-learning software.

This lesson was created by RootMath.

The state of the field regarding the diagnosis and treatment of major depressive disorder (MDD) is discussed. Current challenges and opportunities facing the research and clinical communities are outlined, including appropriate quantitative and qualitative analyses of the heterogeneity of biological, social, and psychiatric factors which may contribute to MDD.

This lesson delves into the opportunities and challenges of telepsychiatry. While novel digital approaches to clinical research and care have the potential to improve and accelerate patient outcomes, researchers and care providers must consider new population factors, such as digital disparity. 

Not long ago, scientists in physiotherapy would claim for the need of big data and large initiatives in the US have already allowed to collect large retrospective data on recovery after brain injury and are working to collect prospective data. In Europe, there is a large field of collaboration in the field of aphasia supported by the European cooperation in Science and Technology that is collecting data on language recovery throughout the world. This lecture discusses recent advances in sharing big data for neurorehabilitation.