This lesson is an overview of the Miniscope project. It will give motivation for why we have developed Miniscopes, how they've been developed, why they may be useful for researchers, and the differences between previous and current versions. While directly applicable to the UCLA Miniscope project, this information can be applied to most mainstream miniature microscopes, including both open source and commercially available models.
This lesson will go through the theory and practical techniques for implanting a GRIN lens for imaging in mice.
Learn how to build a Miniscope and stream data, including an overview of the software involved.
Since their introduction in 2016, the FAIR data principles have gained increasing recognition and adoption in global neuroscience. FAIR defines a set of high-level principles and practices for making digital objects, including data, software, and workflows, Findable, Accessible, Interoperable, and Reusable. But FAIR is not a specification; it leaves many of the specifics up to individual scientific disciplines to define. INCF has been leading the way in promoting, defining, and implementing FAIR data practices for neuroscience. We have been bringing together researchers, infrastructure providers, industry, and publishers through our programs and networks. In this session, we will hear some perspectives on FAIR neuroscience from some of these stakeholders who have been working to develop and use FAIR tools for neuroscience. We will engage in a discussion on questions such as: how is neuroscience doing with respect to FAIR? What have been the successes? What is currently very difficult? Where does neuroscience need to go?
This lecture covers FAIR atlases, from their background, their construction, and how they can be created in line with the FAIR principles.
This lecture provides an introduction to the study of eye-tracking in humans.
This lecture provides an introduction to the application of genetic testing in neurodevelopmental disorders.
GeneWeaver is a web application for the integrated cross-species analysis of functional genomics data to find convergent evidence from heterogeneous sources. The application consists of a large database of gene sets curated from multiple public data resources and curated submissions, along with a suite of analysis tools designed to allow flexible, customized workflows through web-based interactive analysis or scripted API driven analysis. Gene sets come from multiple widely studied species and include ontology annotations, brain gene expression atlases, systems genetic study results, gene regulatory information, pathway databases, drug interaction databases and many other sources. Users can retrieve, store, analyze and share gene sets through a graded access system. Analysis tools are based on combinatorics and statistical methods for comparing, contrasting, and classifying gene sets based on their members.
GeneWeaver is a web application for the integrated cross-species analysis of functional genomics data to find convergent evidence from heterogeneous sources. The application consists of a large database of gene sets curated from multiple public data resources and curated submissions, along with a suite of analysis tools designed to allow flexible, customized workflows through web-based interactive analysis or scripted API driven analysis. Gene sets come from multiple widely studied species and include ontology annotations, brain gene expression atlases, systems genetic study results, gene regulatory information, pathway databases, drug interaction databases and many other sources. Users can retrieve, store, analyze and share gene sets through a graded access system. Analysis tools are based on combinatorics and statistical methods for comparing, contrasting and classifying gene sets based on their members.
This tutorial shows how to use the UCSC genome browser to find a list of genes in a given genomic region.
This tutorial shows how to find all the single nucleotide polymorphisms upstream from genes using the UCSC Genome Browser.
This tutorial demonstrates how to find all the single nucleotide polymorphisms in a gene using the UCSC Genome Browser.
The Saved Sessions feature of the Browser has been around for quite some time, but many of our users have not made full use of it. It offers a great way to keep track of your thinking on a particular topic.
This tutorial demonstrates the visibility controls on the Genome Browser, showing the affect on BED tracks, wiggle tracks and Conservation tracks. It also discusses supertracks and composite tracks.
This tutorial describes the isPCR tool and demonstrates how to use it for predicting the size and location of PCR products and visualizing the genomic location on the genome. The tool operates on DNA templates for all organisms and DNA or RNA on human and mouse. It also demonstrates how to use the Browser to obtain DNA sequences from the genome.
This tutorial describes the dbSNP resources in the UCSC Genome Browser, including display conventions and the subdivision of the data into several useful subset tracks, especially the Common SNPs. There is also a discussion about changes to the genome assemblies from one version to another, and of two ways to navigate between different assemblies of the human genome in the Browser.
This tutorial demonstrates the Data Integrator, a tool that allows combination and intersection of data from up to five primary tables. In the example, data are extracted showing SNPs, genes and phenotypes from a genomic region.
This tutorial shows how to obtain coordinates of genes, then input those coordinates into the Genome Browser for display. The regions do not have to be continuous in the genome.
This tutorial demonstrates the Multi-Region exon-only display mode of the UCSC Genome Browser.