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This lesson continues with the second workshop on reproducible science, focusing on additional open source tools for researchers and data scientists, such as the R programming language for data science, as well as associated tools like RStudio and R Markdown. Additionally, users are introduced to Python and iPython notebooks, Google Colab, and are given hands-on tutorials on how to create a Binder environment, as well as various containers in Docker and Singularity.

Difficulty level: Beginner
Duration: 1:16:04

This lesson contains both a lecture and a tutorial component. The lecture (0:00-20:03 of YouTube video) discusses both the need for intersectional approaches in healthcare as well as the impact of neglecting intersectionality in patient populations. The lecture is followed by a practical tutorial in both Python and R on how to assess intersectional bias in datasets. Links to relevant code and data are found below. 

Difficulty level: Beginner
Duration: 52:26

This lesson gives a description of the BrainHealth Databank, a repository of many types of health-related data, whose aim is to accelerate research, improve care, and to help better understand and diagnose mental illness, as well as develop new treatments and prevention strategies. 

 

This lesson corresponds to slides 46-78 of the PDF below. 

Difficulty level: Beginner
Duration: 1:12:25
Speaker: : Joanna Yu

This lecture covers different perspectives on the study of the mental, focusing on the difference between Mind and Brain. 

Difficulty level: Beginner
Duration: 1:16:30

This lecture covers a lot of post-war developments in the science of the mind, focusing first on the cognitive revolution, and concluding with living machines.

Difficulty level: Beginner
Duration: 2:24:35

This lecture provides an overview of some of the essential concepts in neuropharmacology (e.g. receptor binding, agonism, antagonism), an introduction to pharmacodynamics and pharmacokinetics, and an overview of the drug discovery process relative to diseases of the central nervous system. 

Difficulty level: Beginner
Duration: 45:47

This lecture covers an Introduction to neuron anatomy and signaling, and different types of models, including the Hodgkin-Huxley model.

Difficulty level: Beginner
Duration: 1:23:01
Speaker: : Gaute Einevoll

This lesson gives an introduction to simple spiking neuron models.

Difficulty level: Beginner
Duration: 48 Slides
Speaker: : Zubin Bhuyan

This lesson provides an introduction to simple spiking neuron models.

Difficulty level: Beginner
Duration: 48 Slides
Speaker: : Zubin Bhuyan

The Virtual Brain (TVB) is an open-source, multi-scale, multi-modal brain simulation platform. In this lesson, you get introduced to brain simulation in general and to TVB in particular. This lesson also presents the newest approaches for clinical applications of TVB - that is, for stroke, epilepsy, brain tumors, and Alzheimer’s disease - and show how brain simulation can improve diagnostics, therapy, and understanding of neurological disease.

Difficulty level: Beginner
Duration: 1:35:08
Speaker: : Petra Ritter

This lesson explains the mathematics of neural mass models and their integration to a coupled network. You will also learn about bifurcation analysis, an important technique in the understanding of non-linear systems and as a fundamental method in the design of brain simulations. Lastly, the application of the described mathematics is demonstrated in the exploration of brain stimulation regimes.

Difficulty level: Beginner
Duration: 1:49:24
Speaker: : Andreas Spiegler

In this lesson, the simulation of a virtual epileptic patient is presented as an example of advanced brain simulation as a translational approach to deliver improved clinical results. You will learn about the fundamentals of epilepsy, as well as the concepts underlying epilepsy simulation. By using an iPython notebook, the detailed process of this approach is explained step by step. In the end, you are able to perform simple epilepsy simulations your own.

Difficulty level: Beginner
Duration: 1:28:53
Speaker: : Julie Courtiol

This lecture presents the Graphical (GUI) and Command Line (CLI) User Interface of TVB. Alongside with the speakers, explore and interact with all means necessary to generate, manipulate and visualize connectivity and network dynamics.

Difficulty level: Beginner
Duration: 1:02:16

This lecture briefly introduces The Virtual Brain (TVB), a multi-scale, multi-modal neuroinformatics platform for full brain network simulations using biologically realistic connectivity, as well as its potential neuroscience applications (e.g., epilepsy cases).

Difficulty level: Beginner
Duration: 8:53
Speaker: : Petra Ritter

This lecture introduces the theoretical background and foundations that led to the development of TVB, its architecture, and features of its major software components.

Difficulty level: Beginner
Duration: 46:50
Speaker: : Randy McIntosh

In this tutorial, you will learn how to use TVB-NEST toolbox on your local computer.

Difficulty level: Beginner
Duration: 2:16

This tutorial provides instruction on how to perform multi-scale simulation of Alzheimer's disease on The Virtual Brain Simulation Platform.

Difficulty level: Beginner
Duration: 29:08

This presentation accompanies the paper entitled: An automated pipeline for constructing personalized virtual brains from multimodal neuroimaging data (see link below to download publication). 

Difficulty level: Beginner
Duration: 4:56

This lecture provides an overview of successful open-access projects aimed at describing complex neuroscientific models, and makes a case for expanded use of resources in support of reproducibility and validation of models against experimental data.

Difficulty level: Beginner
Duration: 1:00:39
Speaker: : Sharon Crook

This lesson provides a brief overview of the Python programming language, with an emphasis on tools relevant to data scientists.

Difficulty level: Beginner
Duration: 1:16:36
Speaker: : Tal Yarkoni