Research Resource Identifiers (RRIDs) are ID numbers assigned to help researchers cite key resources (antibodies, model organisms and software projects) in the biomedical literature to improve transparency of research methods.
Computational models provide a framework for integrating data across spatial scales and for exploring hypotheses about the biological mechanisms underlying neuronal and network dynamics. However, as models increase in complexity, additional barriers emerge to the creation, exchange, and re-use of models. Successful projects have created standards for describing complex models in neuroscience and provide open source tools to address these issues. This lecture provides an overview of these projects and make a case for expanded use of resources in support of reproducibility and validation of models against experimental data.
NWB: An ecosystem for neurophysiology data standardization
Félix-Antoine Fortin from Calcul Québec gives an introduction to high-performance computing with the Compute Canada network, first providing an overview of use cases for HPC and then a hand-on tutorial. Though some examples might seem specific to the Calcul Québec, all computing clusters in the Compute Canada network share the same software modules and environments.
The lesson was given in the context of the BrainHack School 2020.
The Canadian Open Neuroscience Platform (CONP) Portal is a web interface that facilitates open science for the neuroscience community by simplifying global access to and sharing of datasets and tools. The Portal internalizes the typical cycle of a research project, beginning with data acquisition, followed by data processing with published tools, and ultimately the publication of results with a link to the original dataset.
In this video, Samir Das and Tristan Glatard give a short overview of the main features of the CONP Portal.
Shawn Brown presents an overview of CBRAIN, a web-based platform that allows neuroscientists to perform computationally intensive data analyses by connecting them to high-performance-computing facilities across Canada and around the world.
This talk was given in the context of a Ludmer Centre event in 2019.
This course will teach you AWS basics right through to advanced cloud computing concepts. There are lots of hands-on exercises using an AWS free tier account to give you practical experience with Amazon Web Services. Visual slides and animations will help you gain a deep understanding of Cloud Computing.
This lesson is courtesy of freeCodeCamp.
Lecture on functional brain parcellations and a set of tutorials on bootstrap agregation of stable clusters (BASC) for fMRI brain parcellation which were part of the 2019 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.
As models in neuroscience have become increasingly complex, it has become more difficult to share all aspects of models and model analysis, hindering model accessibility and reproducibility. In this session, we will discuss existing resources for promoting FAIR data and models in computational neuroscience, their impact on the field, and the remaining barriers. This lecture covers how FAIR practices affect personalized data models, including workflows, challenges, and how to improve these practices.
Much like neuroinformatics, data science uses techniques from computational science to derive meaningful results from large complex datasets. In this session, we will explore the relationship between neuroinformatics and data science, by emphasizing a range of data science approaches and activities, ranging from the development and application of statistical methods, through the establishment of communities and platforms, and through the implementation of open-source software tools. Rather than rigid distinctions, in the data science of neuroinformatics, these activities and approaches intersect and interact in dynamic ways. Together with a panel of cutting-edge neuro-data-scientist speakers, we will explore these dynamics
This lecture covers how brainlife.io works, and how it can be applied to neuroscience data.
Since their introduction in 2016, the FAIR data principles have gained increasing recognition and adoption in global neuroscience. FAIR defines a set of high-level principles and practices for making digital objects, including data, software, and workflows, Findable, Accessible, Interoperable, and Reusable. But FAIR is not a specification; it leaves many of the specifics up to individual scientific disciplines to define. INCF has been leading the way in promoting, defining, and implementing FAIR data practices for neuroscience. We have been bringing together researchers, infrastructure providers, industry, and publishers through our programs and networks. In this session, we will hear some perspectives on FAIR neuroscience from some of these stakeholders who have been working to develop and use FAIR tools for neuroscience. We will engage in a discussion on questions such as: how is neuroscience doing with respect to FAIR? What have been the successes? What is currently very difficult? Where does neuroscience need to go?
This lecture covers FAIR atlases, from their background, their construction, and how they can be created in line with the FAIR principles.
Tutorial describing the basic search and navigation features of the Allen Mouse Brain Atlas
Tutorial describing the basic search and navigation features of the Allen Developing Mouse Brain Atlas
This tutorial demonstrates how to use the differential search feature of the Allen Mouse Brain Atlas to find gene markers for different regions of the brain and to visualize this gene expression in three-dimensional space. Differential search is also available for the Allen Developing Mouse Brain Atlas and the Allen Human Brain Atlas.
GeneWeaver is a web application for the integrated cross-species analysis of functional genomics data to find convergent evidence from heterogeneous sources. The application consists of a large database of gene sets curated from multiple public data resources and curated submissions, along with a suite of analysis tools designed to allow flexible, customized workflows through web-based interactive analysis or scripted API driven analysis. Gene sets come from multiple widely studied species and include ontology annotations, brain gene expression atlases, systems genetic study results, gene regulatory information, pathway databases, drug interaction databases and many other sources. Users can retrieve, store, analyze and share gene sets through a graded access system. Analysis tools are based on combinatorics and statistical methods for comparing, contrasting and classifying gene sets based on their members.
This tutorial shows how to use the UCSC genome browser to find a list of genes in a given genomic region.
This tutorial shows how to find all the single nucleotide polymorphisms upstream from genes using the UCSC Genome Browser.