Tutorial describing the basic search and navigation features of the Allen Mouse Brain Atlas
Tutorial describing the basic search and navigation features of the Allen Developing Mouse Brain Atlas
This tutorial demonstrates how to use the differential search feature of the Allen Mouse Brain Atlas to find gene markers for different regions of the brain and to visualize this gene expression in three-dimensional space. Differential search is also available for the Allen Developing Mouse Brain Atlas and the Allen Human Brain Atlas.
The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.
GeneWeaver is a web application for the integrated cross-species analysis of functional genomics data to find convergent evidence from heterogeneous sources. The application consists of a large database of gene sets curated from multiple public data resources and curated submissions, along with a suite of analysis tools designed to allow flexible, customized workflows through web-based interactive analysis or scripted API driven analysis. Gene sets come from multiple widely studied species and include ontology annotations, brain gene expression atlases, systems genetic study results, gene regulatory information, pathway databases, drug interaction databases and many other sources. Users can retrieve, store, analyze and share gene sets through a graded access system. Analysis tools are based on combinatorics and statistical methods for comparing, contrasting and classifying gene sets based on their members.
Félix-Antoine Fortin from Calcul Québec gives an introduction to high-performance computing with the Compute Canada network, first providing an overview of use cases for HPC and then a hand-on tutorial. Though some examples might seem specific to the Calcul Québec, all computing clusters in the Compute Canada network share the same software modules and environments.
The lesson was given in the context of the BrainHack School 2020.
The Canadian Open Neuroscience Platform (CONP) Portal is a web interface that facilitates open science for the neuroscience community by simplifying global access to and sharing of datasets and tools. The Portal internalizes the typical cycle of a research project, beginning with data acquisition, followed by data processing with published tools, and ultimately the publication of results with a link to the original dataset.
In this video, Samir Das and Tristan Glatard give a short overview of the main features of the CONP Portal.
Shawn Brown presents an overview of CBRAIN, a web-based platform that allows neuroscientists to perform computationally intensive data analyses by connecting them to high-performance-computing facilities across Canada and around the world.
This talk was given in the context of a Ludmer Centre event in 2019.
This course will teach you AWS basics right through to advanced cloud computing concepts. There are lots of hands-on exercises using an AWS free tier account to give you practical experience with Amazon Web Services. Visual slides and animations will help you gain a deep understanding of Cloud Computing.
This lesson is courtesy of freeCodeCamp.
As models in neuroscience have become increasingly complex, it has become more difficult to share all aspects of models and model analysis, hindering model accessibility and reproducibility. In this session, we will discuss existing resources for promoting FAIR data and models in computational neuroscience, their impact on the field, and the remaining barriers. This lecture covers how FAIR practices affect personalized data models, including workflows, challenges, and how to improve these practices.
Much like neuroinformatics, data science uses techniques from computational science to derive meaningful results from large complex datasets. In this session, we will explore the relationship between neuroinformatics and data science, by emphasizing a range of data science approaches and activities, ranging from the development and application of statistical methods, through the establishment of communities and platforms, and through the implementation of open-source software tools. Rather than rigid distinctions, in the data science of neuroinformatics, these activities and approaches intersect and interact in dynamic ways. Together with a panel of cutting-edge neuro-data-scientist speakers, we will explore these dynamics
This lecture covers how brainlife.io works, and how it can be applied to neuroscience data.
In this presentation by the OHBM OpenScienceSIG, Tom Shaw and Steffen Bollmann cover how containers can be useful for running the same software on different platforms and sharing analysis pipelines with other researchers. They demonstrate how to build docker containers from scratch, using Neurodocker, and cover how to use containers on an HPC with singularity.
Since their introduction in 2016, the FAIR data principles have gained increasing recognition and adoption in global neuroscience. FAIR defines a set of high-level principles and practices for making digital objects, including data, software, and workflows, Findable, Accessible, Interoperable, and Reusable. But FAIR is not a specification; it leaves many of the specifics up to individual scientific disciplines to define. INCF has been leading the way in promoting, defining, and implementing FAIR data practices for neuroscience. We have been bringing together researchers, infrastructure providers, industry, and publishers through our programs and networks. In this session, we will hear some perspectives on FAIR neuroscience from some of these stakeholders who have been working to develop and use FAIR tools for neuroscience. We will engage in a discussion on questions such as: how is neuroscience doing with respect to FAIR? What have been the successes? What is currently very difficult? Where does neuroscience need to go?
This lecture covers FAIR atlases, from their background, their construction, and how they can be created in line with the FAIR principles.
EyeWire is a game to map the brain. Players are challenged to map branches of a neuron from one side of a cube to the other in a 3D puzzle. Players scroll through the cube and reconstruct neurons with the help of an artificial intelligence algorithm developed at Seung Lab in Princeton University. EyeWire gameplay advances neuroscience by helping researchers discover how neurons connect to process visual information.
This module explains how neurons come together to create the networks that give rise to our thoughts. The totality of our neurons and their connection is called our connectome. Learn how this connectome changes as we learn, and computes information. We will also learn about physiological phenomena of the brain such as synchronicity that gives rise to brain waves.
NWB: An ecosystem for neurophysiology data standardization
Learn how to build and share extensions in NWB