The Virtual Brain is an open-source, multi-scale, multi-modal brain simulation platform. In this lesson, you get introduced to brain simulation in general and to The Virtual brain in particular. Prof. Ritter will present the newest approaches for clinical applications of The Virtual brain - that is, for stroke, epilepsy, brain tumors and Alzheimer’s disease - and show how brain simulation can improve diagnostics, therapy and understanding of neurological disease.
The concept of neural masses, an application of mean field theory, is introduced as a possible surrogate for electrophysiological signals in brain simulation. The mathematics of neural mass models and their integration to a coupled network are explained. Bifurcation analysis is presented as an important technique in the understanding of non-linear systems and as a fundamental method in the design of brain simulations. Finally, the application of the described mathematics is demonstrated in the exploration of brain stimulation regimes.
The simulation of the virtual epileptic patient is presented as an example of advanced brain simulation as a translational approach to deliver improved results in clinics. The fundamentals of epilepsy are explained. On this basis, the concept of epilepsy simulation is developed. By using an iPython notebook, the detailed process of this approach is explained step by step. In the end, you are able to perform simple epilepsy simulations your own.
The practical usage of The Virtual brain in its graphical user interface and via python scripts is introduced. In the graphical user interface, you are guided through its data repository, simulator, phase plane exploration tool, connectivity editor, stimulus generator and the provided analyses. The implemented iPython notebooks of TVB are presented, and since they are public, can be used for further exploration of The Virtual brain.
A brief overview of the Python programming language, with an emphasis on tools relevant to data scientists. This lecture was part of the 2018 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.
Colt Steele provides a comprehensive introduction to the command line and 50 popular Linux commands. This is a long course (nearly 5 hours) but well worth it if you are going to spend a good part of your career working from a terminal, which is likely if you are interested in flexibility, power, and reproducibility in neuroscience research.
This lesson is courtesy of freeCodeCamp.
Félix-Antoine Fortin from Calcul Québec gives an introduction to high-performance computing with the Compute Canada network, first providing an overview of use cases for HPC and then a hand-on tutorial. Though some examples might seem specific to the Calcul Québec, all computing clusters in the Compute Canada network share the same software modules and environments.
The lesson was given in the context of the BrainHack School 2020.
The Canadian Open Neuroscience Platform (CONP) Portal is a web interface that facilitates open science for the neuroscience community by simplifying global access to and sharing of datasets and tools. The Portal internalizes the typical cycle of a research project, beginning with data acquisition, followed by data processing with published tools, and ultimately the publication of results with a link to the original dataset.
In this video, Samir Das and Tristan Glatard give a short overview of the main features of the CONP Portal.
Shawn Brown presents an overview of CBRAIN, a web-based platform that allows neuroscientists to perform computationally intensive data analyses by connecting them to high-performance-computing facilities across Canada and around the world.
This talk was given in the context of a Ludmer Centre event in 2019.
This course will teach you AWS basics right through to advanced cloud computing concepts. There are lots of hands-on exercises using an AWS free tier account to give you practical experience with Amazon Web Services. Visual slides and animations will help you gain a deep understanding of Cloud Computing.
This lesson is courtesy of freeCodeCamp.
Lecture on functional brain parcellations and a set of tutorials on bootstrap agregation of stable clusters (BASC) for fMRI brain parcellation which were part of the 2019 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.
Neuronify is an educational tool meant to create intuition for how neurons and neural networks behave. You can use it to combine neurons with different connections, just like the ones we have in our brain, and explore how changes on single cells lead to behavioral changes in important networks. Neuronify is based on an integrate-and-fire model of neurons. This is one of the simplest models of neurons that exist. It focuses on the spike timing of a neuron and ignores the details of the action potential dynamics. These neurons are modeled as simple RC circuits. When the membrane potential is above a certain threshold, a spike is generated and the voltage is reset to its resting potential. This spike then signals other neurons through its synapses.
Neuronify aims to provide a low entry point to simulation-based neuroscience.
Since their introduction in 2016, the FAIR data principles have gained increasing recognition and adoption in global neuroscience. FAIR defines a set of high-level principles and practices for making digital objects, including data, software, and workflows, Findable, Accessible, Interoperable, and Reusable. But FAIR is not a specification; it leaves many of the specifics up to individual scientific disciplines to define. INCF has been leading the way in promoting, defining, and implementing FAIR data practices for neuroscience. We have been bringing together researchers, infrastructure providers, industry, and publishers through our programs and networks. In this session, we will hear some perspectives on FAIR neuroscience from some of these stakeholders who have been working to develop and use FAIR tools for neuroscience. We will engage in a discussion on questions such as: how is neuroscience doing with respect to FAIR? What have been the successes? What is currently very difficult? Where does neuroscience need to go?
This lecture covers FAIR atlases, from their background, their construction, and how they can be created in line with the FAIR principles.
As models in neuroscience have become increasingly complex, it has become more difficult to share all aspects of models and model analysis, hindering model accessibility and reproducibility. In this session, we will discuss existing resources for promoting FAIR data and models in computational neuroscience, their impact on the field, and the remaining barriers. This lecture covers how to make modeling workflows FAIR by working through a practical example, dissecting the steps within the workflow, and detailing the tools and resources used at each step.
As models in neuroscience have become increasingly complex, it has become more difficult to share all aspects of models and model analysis, hindering model accessibility and reproducibility. In this session, we will discuss existing resources for promoting FAIR data and models in computational neuroscience, their impact on the field, and the remaining barriers. This lecture covers the structured validation process within computational neuroscience, including the tools, services, and methods involved in simulation and analysis.
The course is an introduction to the field of electrophysiology standards, infrastructure, and initiatives. This lecture discusses the FAIR principles as they apply to electrophysiology data and metadata, the building blocks for community tools and standards, platforms and grassroots initiatives, and the challenges therein.
This session provides users with an introduction to tools and resources that facilitate the implementation of FAIR in their research.
This session will include presentations of infrastructure that embrace the FAIR principles developed by members of the INCF Community.
This lecture provides an overview of The Virtual Brain Simulation Platform.
Demo of the BRIAN Simulator. BRIAN is a free, open source simulator for spiking neural networks. It is written in the Python programming language and is available on almost all platforms. We believe that a simulator should not only save the time of processors, but also the time of scientists. Brian is therefore designed to be easy to learn and use, highly flexible and easily extensible.
NeuroFedora is a volunteer driven initiative to provide a ready to use Fedora based Free/Open Source Software platform for neuroscience. We believe that similar to Free Software, science should be free for all to use, share, modify, and study. The use of Free Software also aids reproducibility, data sharing, and collaboration in the research community. By making the tools used in the scientific process easier to use, NeuroFedora aims to take a step to enable this ideal. The CompNeuro Fedora Lab was specially to enable computational neuroscience. It includes everything you will need to get your work done—modelling software, analysis tools, general productivity tools—all well integrated with the modern GNOME platform to give you a complete operating system.