Tutorial describing the basic search and navigation features of the Allen Mouse Brain Atlas
Tutorial describing the basic search and navigation features of the Allen Developing Mouse Brain Atlas
This tutorial demonstrates how to use the differential search feature of the Allen Mouse Brain Atlas to find gene markers for different regions of the brain and to visualize this gene expression in three-dimensional space. Differential search is also available for the Allen Developing Mouse Brain Atlas and the Allen Human Brain Atlas.
The Mouse Phenome Database (MPD) provides access to primary experimental trait data, genotypic variation, protocols and analysis tools for mouse genetic studies. Data are contributed by investigators worldwide and represent a broad scope of phenotyping endpoints and disease-related traits in naïve mice and those exposed to drugs, environmental agents or other treatments. MPD ensures rigorous curation of phenotype data and supporting documentation using relevant ontologies and controlled vocabularies. As a repository of curated and integrated data, MPD provides a means to access/re-use baseline data, as well as allows users to identify sensitized backgrounds for making new mouse models with genome editing technologies, analyze trait co-inheritance, benchmark assays in their own laboratories, and many other research applications. MPD’s primary source of funding is NIDA. For this reason, a majority of MPD data is neuro- and behavior-related.
GeneWeaver is a web application for the integrated cross-species analysis of functional genomics data to find convergent evidence from heterogeneous sources. The application consists of a large database of gene sets curated from multiple public data resources and curated submissions, along with a suite of analysis tools designed to allow flexible, customized workflows through web-based interactive analysis or scripted API driven analysis. Gene sets come from multiple widely studied species and include ontology annotations, brain gene expression atlases, systems genetic study results, gene regulatory information, pathway databases, drug interaction databases and many other sources. Users can retrieve, store, analyze and share gene sets through a graded access system. Analysis tools are based on combinatorics and statistical methods for comparing, contrasting and classifying gene sets based on their members.
Lecture on functional brain parcellations and a set of tutorials on bootstrap agregation of stable clusters (BASC) for fMRI brain parcellation which were part of the 2019 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.
As models in neuroscience have become increasingly complex, it has become more difficult to share all aspects of models and model analysis, hindering model accessibility and reproducibility. In this session, we will discuss existing resources for promoting FAIR data and models in computational neuroscience, their impact on the field, and the remaining barriers
This lecture covers how to make modeling workflows FAIR by working through a practical example, dissecting the steps within the workflow, and detailing the tools and resources used at each step.
This session will explore some practical use cases and see whether these affect your repository, your tool, or your research.
Demo of the BRIAN Simulator. BRIAN is a free, open source simulator for spiking neural networks. It is written in the Python programming language and is available on almost all platforms. We believe that a simulator should not only save the time of processors, but also the time of scientists. Brian is therefore designed to be easy to learn and use, highly flexible and easily extensible.
NeuroFedora is a volunteer driven initiative to provide a ready to use Fedora based Free/Open Source Software platform for neuroscience. We believe that similar to Free Software, science should be free for all to use, share, modify, and study. The use of Free Software also aids reproducibility, data sharing, and collaboration in the research community. By making the tools used in the scientific process easier to use, NeuroFedora aims to take a step to enable this ideal. The CompNeuro Fedora Lab was specially to enable computational neuroscience. It includes everything you will need to get your work done—modelling software, analysis tools, general productivity tools—all well integrated with the modern GNOME platform to give you a complete operating system.
neurolib is a computational framework for simulating coupled neural mass models written in Python. It helps you to easily load structural brain scan data to construct brain networks where each node is a neural mass representing a single brain area. This network model can be used to simulate whole-brain dynamics. neurolib provides a simulation and optimization framework which allows you to easily implement your own neural mass model, simulate fMRI BOLD activity, analyse the results and fit your model to empirical data.
GeNN (GPU-enhanced Neuronal Networks) framework, which aims to facilitate the use of graphics accelerators for computational models of large-scale neuronal networks to address this challenge. GeNN is an open source library that generates code to accelerate the execution of network simulations on NVIDIA GPUs, through a flexible and extensible interface, which does not require in-depth technical knowledge from the users.
This video gives a short introduction to the EBRAINS data sharing platform, why it was developed, and how it contributes to open data sharing.
This video demonstrates how to find, access, and download data on EBRAINS.
Peer Herholz gives a tour of how popular virtualization tools like Docker and Singularity are playing a crucial role in improving reproducibility and enabling high-performance computing in neuroscience.
Introduction to the types of glial cells, homeostasis (influence of cerebral blood flow and influence on neurons), insulation and protection of axons (myelin sheath; nodes of Ranvier), microglia and reactions of the CNS to injury.
Learn how to handle writing very large data in MatNWB
The course is an introduction to the field of electrophysiology standards, infrastructure, and initiatives.
This lecture discusses the FAIR principles as they apply to electrophysiology data and metadata, the building blocks for community tools and standards, platforms and grassroots initiatives, and the challenges therein.