Brief introduction to Research Resource Identifiers (RRIDs), persistent and unique identifiers for referencing a research resource.
Research Resource Identifiers (RRIDs) are ID numbers assigned to help researchers cite key resources (antibodies, model organisms and software projects) in the biomedical literature to improve transparency of research methods.
The Brain Imaging Data Structure (BIDS) is a standard prescribing a formal way to name and organize MRI data and metadata in a file system that simplifies communication and collaboration between users and enables easier data validation and software development through using consistent paths and naming for data files.
Neurodata Without Borders (NWB) is a data standard for neurophysiology that provides neuroscientists with a common standard to share, archive, use, and build common analysis tools for neurophysiology data.
The Neuroimaging Data Model (NIDM) is a collection of specification documents that define extensions the W3C PROV standard for the domain of human brain mapping. NIDM uses provenance information as means to link components from different stages of the scientific research process from dataset descriptors and computational workflow, to derived data and publication.
Neuroscience Information Exchange (NIX) Format data model allows storing fully annotated scientific datasets, i.e. the data together with rich metadata and their relations in a consistent, comprehensive format. Its aim is to achieve standardization by providing a common data structure and APIs for a multitude of data types and use cases, focused on but not limited to neuroscience. In contrast to most other approaches, the NIX approach is to achieve this flexibility with a minimum set of data model elements.
Computational models provide a framework for integrating data across spatial scales and for exploring hypotheses about the biological mechanisms underlying neuronal and network dynamics. However, as models increase in complexity, additional barriers emerge to the creation, exchange, and re-use of models. Successful projects have created standards for describing complex models in neuroscience and provide open source tools to address these issues. This lecture provides an overview of these projects and make a case for expanded use of resources in support of reproducibility and validation of models against experimental data.
NWB: An ecosystem for neurophysiology data standardization
Lecture on functional brain parcellations and a set of tutorials on bootstrap agregation of stable clusters (BASC) for fMRI brain parcellation which were part of the 2019 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.
Neuronify is an educational tool meant to create intuition for how neurons and neural networks behave. You can use it to combine neurons with different connections, just like the ones we have in our brain, and explore how changes on single cells lead to behavioral changes in important networks. Neuronify is based on an integrate-and-fire model of neurons. This is one of the simplest models of neurons that exist. It focuses on the spike timing of a neuron and ignores the details of the action potential dynamics. These neurons are modeled as simple RC circuits. When the membrane potential is above a certain threshold, a spike is generated and the voltage is reset to its resting potential. This spike then signals other neurons through its synapses.
Neuronify aims to provide a low entry point to simulation-based neuroscience.
This lecture covers structured data, databases, federating neuroscience-relevant databases, ontologies.
Since their introduction in 2016, the FAIR data principles have gained increasing recognition and adoption in global neuroscience. FAIR defines a set of high-level principles and practices for making digital objects, including data, software, and workflows, Findable, Accessible, Interoperable, and Reusable. But FAIR is not a specification; it leaves many of the specifics up to individual scientific disciplines to define. INCF has been leading the way in promoting, defining, and implementing FAIR data practices for neuroscience. We have been bringing together researchers, infrastructure providers, industry, and publishers through our programs and networks. In this session, we will hear some perspectives on FAIR neuroscience from some of these stakeholders who have been working to develop and use FAIR tools for neuroscience. We will engage in a discussion on questions such as: how is neuroscience doing with respect to FAIR? What have been the successes? What is currently very difficult? Where does neuroscience need to go?
This lecture covers FAIR atlases, from their background, their construction, and how they can be created in line with the FAIR principles.
This talk highlights a set of platform technologies, software, and data collections that close and shorten the feedback cycle in research.
An agent for reproducible neuroimaging
The Human Connectome Project aims to provide an unparalleled compilation of neural data, an interface to graphically navigate this data and the opportunity to achieve never before realized conclusions about the living human brain.
As models in neuroscience have become increasingly complex, it has become more difficult to share all aspects of models and model analysis, hindering model accessibility and reproducibility. In this session, we will discuss existing resources for promoting FAIR data and models in computational neuroscience, their impact on the field, and the remaining barriers. This lecture covers how to make modeling workflows FAIR by working through a practical example, dissecting the steps within the workflow, and detailing the tools and resources used at each step.
As models in neuroscience have become increasingly complex, it has become more difficult to share all aspects of models and model analysis, hindering model accessibility and reproducibility. In this session, we will discuss existing resources for promoting FAIR data and models in computational neuroscience, their impact on the field, and the remaining barriers. This lecture covers the structured validation process within computational neuroscience, including the tools, services, and methods involved in simulation and analysis.
The course is an introduction to the field of electrophysiology standards, infrastructure, and initiatives. This lecture discusses the FAIR principles as they apply to electrophysiology data and metadata, the building blocks for community tools and standards, platforms and grassroots initiatives, and the challenges therein.
This session provides users with an introduction to tools and resources that facilitate the implementation of FAIR in their research.
This session will include presentations of infrastructure that embrace the FAIR principles developed by members of the INCF Community.
This lecture provides an overview of The Virtual Brain Simulation Platform.